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    GAMT1 S-adenosyl-L-methionine-dependent methyltransferases superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828748, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GAMT1
    Official Full Name
    S-adenosyl-L-methionine-dependent methyltransferases superfamily protein
    Primary source
    TAIR:AT4G26420
    Locus tag
    AT4G26420
    See related
    Araport:AT4G26420
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtGAMT1; gibberellin methyltransferase 1; M3E9.150; M3E9_150
    Summary
    A member of the Arabidopsis SABATH methyltransferase gene family. Encodes GAMT1, a methyltransferase that uses S-adenosine-L-methionine (SAM) as a methyl donor to methylate the carboxyl group of GAs, resulting in the methyl esters of GAs (MeGAs). Expressed most highly in the siliques during seed development.
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    Genomic context

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    See GAMT1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    3
    Sequence:
    Chromosome: 4; NC_003075.7 (13350796..13352569, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Pyruvate kinase family protein Neighboring gene RING/U-box superfamily protein Neighboring gene chromosome-associated kinesin Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene COP9 signalosome subunit 6B Neighboring gene WRKY DNA-binding protein 34

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis gibberellin methyl transferase 1 suppresses gibberellin activity, reduces whole-plant transpiration and promotes drought tolerance in transgenic tomato. Nir I, et al. Plant Cell Environ, 2014 Jan. PMID 23668385
    2. Methylation of gibberellins by Arabidopsis GAMT1 and GAMT2. Varbanova M, et al. Plant Cell, 2007 Jan. PMID 17220201, Free PMC Article
    3. Elucidation of the final reactions of DIMBOA-glucoside biosynthesis in maize: characterization of Bx6 and Bx7. Jonczyk R, et al. Plant Physiol, 2008 Mar. PMID 18192444, Free PMC Article
    4. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Tomato plants overexpressing AtGAMT1 exhibited typical GA-deficiency phenotypes and increased tolerance to drought stress.
      Title: The Arabidopsis gibberellin methyl transferase 1 suppresses gibberellin activity, reduces whole-plant transpiration and promotes drought tolerance in transgenic tomato.
    2. GAMT1 and GAMT2 encode enzymes that use S-adenosine-L-methionine (SAM) as a methyl donor to methylate the carboxyl group of GAs. Both genes are expressed most highly in the siliques during seed development. [GAMT1]
      Title: Methylation of gibberellins by Arabidopsis GAMT1 and GAMT2.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    NM_001125589.5
    NM_001341798.1
    NM_118775.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables S-adenosylmethionine-dependent methyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables gibberellin A9 carboxyl methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables gibberellin carboxyl-O-methyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within methylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    S-adenosyl-L-methionine-dependent methyltransferases superfamily protein
    NP_001119061.1
    • GAMT1; CONTAINS InterPro DOMAIN/s: SAM dependent carboxyl methyltransferase (InterPro:IPR005299); BEST Arabidopsis thaliana protein match is: gibberellic acid methyltransferase 2 (TAIR:AT5G56300.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_194372.2
    • GAMT1; CONTAINS InterPro DOMAIN/s: SAM dependent carboxyl methyltransferase (InterPro:IPR005299); BEST Arabidopsis thaliana protein match is: gibberellic acid methyltransferase 2 (TAIR:AT5G56300.1); Has 916 Blast hits to 905 proteins in 122 species: Archae - 0; Bacteria - 67; Metazoa - 9; Fungi - 3; Plants - 723; Viruses - 0; Other Eukaryotes - 114 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      13350796..13352569 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118775.3 → NP_194372.2  S-adenosyl-L-methionine-dependent methyltransferases superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194372.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3H6L1, F4JUY5, O65592, Q56Z47
      UniProtKB/TrEMBL
      A0A5S9XW22, A0A654FT19
      Conserved Domains (1) summary
      pfam03492
      Location:43 → 371
      Methyltransf_7; SAM dependent carboxyl methyltransferase

    2. NM_001125589.5 → NP_001119061.1  S-adenosyl-L-methionine-dependent methyltransferases superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001119061.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4JUY5
      Conserved Domains (1) summary
      pfam03492
      Location:31 → 245
      Methyltransf_7; SAM dependent carboxyl methyltransferase

    3. NM_001341798.1 → NP_001329462.1  S-adenosyl-L-methionine-dependent methyltransferases superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B7R9
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4JUY5.1

    Gene LinkOut

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