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    DHS2 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829489, updated on 18-Sep-2024

    Summary

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    Official Symbol
    DHS2
    Official Full Name
    3-deoxy-d-arabino-heptulosonate 7-phosphate synthase
    Primary source
    TAIR:AT4G33510
    Locus tag
    AT4G33510
    See related
    Araport:AT4G33510
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    3-deoxy-d-arabino-heptulosonate 7-phosphate synthase; 3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE; 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE 2; AtDAHP2; DAHP2; F17M5.270; F17M5_270
    Summary
    Enzyme catalyzing the first committed step in aromatic amino acid biosynthesis
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    Genomic context

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    See DHS2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    4
    Sequence:
    Chromosome: 4; NC_003075.7 (16116371..16118825)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene BTB/POZ domain protein TNFAIP protein Neighboring gene Eukaryotic aspartyl protease family protein Neighboring gene Protein phosphatase 2C family protein Neighboring gene Ubiquitin carboxyl-terminal hydrolase family protein Neighboring gene P-type ATP-ase 1 Neighboring gene K+ uptake permease 5 Neighboring gene metallo-beta-lactamase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Differential induction of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase genes in Arabidopsis thaliana by wounding and pathogenic attack. Keith B, et al. Proc Natl Acad Sci U S A, 1991 Oct 1. PMID 1681544, Free PMC Article
    2. Arabidopsis TRANSCURVATA1 encodes NUP58, a component of the nucleopore central channel. Ferrández-Ayela A, et al. PLoS One, 2013. PMID 23840761, Free PMC Article
    3. Redox Conformation-Specific Protein-Protein Interactions of the 2-Cysteine Peroxiredoxin in Arabidopsis. Liebthal M, et al. Antioxidants (Basel), 2020 Jun 11. PMID 32545358, Free PMC Article
    4. Proteomic profiling of tandem affinity purified 14-3-3 protein complexes in Arabidopsis thaliana. Chang IF, et al. Proteomics, 2009 Jun. PMID 19452453, Free PMC Article
    5. AT_CHLORO, a comprehensive chloroplast proteome database with subplastidial localization and curated information on envelope proteins. Ferro M, et al. Mol Cell Proteomics, 2010 Jun. PMID 20061580, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001342217.1
    NM_119505.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 3-deoxy-7-phosphoheptulonate synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables 3-deoxy-7-phosphoheptulonate synthase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within aromatic amino acid family biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in chorismate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within chorismate biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in chloroplast thylakoid HDA PubMed 
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    3-deoxy-d-arabino-heptulosonate 7-phosphate synthase
    NP_001320125.1
    • 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase (DHS2); FUNCTIONS IN: protein binding, 3-deoxy-7-phosphoheptulonate synthase activity; INVOLVED IN: chorismate biosynthetic process, aromatic amino acid family biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: DAHP synthetase, class II (InterPro:IPR002480); BEST Arabidopsis thaliana protein match is: Class-II DAHP synthetase family protein (TAIR:AT1G22410.1); Has 3601 Blast hits to 3584 proteins in 682 species: Archae - 0; Bacteria - 1231; Metazoa - 0; Fungi - 107; Plants - 172; Viruses - 0; Other Eukaryotes - 2091 (source: NCBI BLink).
    NP_195077.1
    • 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase (DHS2); FUNCTIONS IN: protein binding, 3-deoxy-7-phosphoheptulonate synthase activity; INVOLVED IN: chorismate biosynthetic process, aromatic amino acid family biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: DAHP synthetase, class II (InterPro:IPR002480); BEST Arabidopsis thaliana protein match is: Class-II DAHP synthetase family protein (TAIR:AT1G22410.1); Has 3818 Blast hits to 3801 proteins in 685 species: Archae - 0; Bacteria - 1238; Metazoa - 0; Fungi - 112; Plants - 173; Viruses - 0; Other Eukaryotes - 2295 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      16116371..16118825
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119505.3 → NP_195077.1  3-deoxy-d-arabino-heptulosonate 7-phosphate synthase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195077.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q00218, Q9SZC8
      UniProtKB/TrEMBL
      A0A178US70, A0A5S9XYA1, A0A7G2F9I3, Q8LAR5
      Conserved Domains (1) summary
      PLN02291
      Location:34 → 506
      PLN02291; phospho-2-dehydro-3-deoxyheptonate aldolase

    2. NM_001342217.1 → NP_001320125.1  3-deoxy-d-arabino-heptulosonate 7-phosphate synthase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4JIZ3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q00218.2

    Gene LinkOut

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