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    HERK1 hercules receptor kinase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 823774, updated on 18-Sep-2024

    Summary

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    Official Symbol
    HERK1
    Official Full Name
    hercules receptor kinase 1
    Primary source
    TAIR:AT3G46290
    Locus tag
    AT3G46290
    See related
    Araport:AT3G46290
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    hercules receptor kinase 1
    Summary
    Encodes HERCULES1 (HERK1), a receptor kinase regulated by Brassinosteroids and required for cell elongation during vegetative growth.
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    Genomic context

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    See HERK1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    2
    Sequence:
    Chromosome: 3; NC_003074.8 (17012500..17015885)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene receptor protein kinase-like protein Neighboring gene kinase-like protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional analysis of related CrRLK1L receptor-like kinases in pollen tube reception. Kessler SA, et al. EMBO Rep, 2015 Jan. PMID 25490905, Free PMC Article
    2. A family of receptor-like kinases are regulated by BES1 and involved in plant growth in Arabidopsis thaliana. Guo H, et al. Plant Signal Behav, 2009 Aug. PMID 19820315, Free PMC Article
    3. Three related receptor-like kinases are required for optimal cell elongation in Arabidopsis thaliana. Guo H, et al. Proc Natl Acad Sci U S A, 2009 May 5. PMID 19383785, Free PMC Article
    4. CrRLK1L receptor-like kinases HERK1 and ANJEA are female determinants of pollen tube reception. Galindo-Trigo S, et al. EMBO Rep, 2020 Feb 5. PMID 31867824, Free PMC Article
    5. RALF peptide signaling controls the polytubey block in Arabidopsis. Zhong S, et al. Science, 2022 Jan 21. PMID 35050671, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CrRLK1L receptor-like kinases HERK1 and ANJEA are female determinants of pollen tube reception.
      Title: CrRLK1L receptor-like kinases HERK1 and ANJEA are female determinants of pollen tube reception.
    2. Extracellular domains of the FER, ANX1 and HERK1 receptor-like kinases are not interchangeable for their function in pollen tube reception, but their intracellular domains are.
      Title: Functional analysis of related CrRLK1L receptor-like kinases in pollen tube reception.
    3. 3 related receptor-like kinases, HERCULES1, THESEUS1, and FERONIA, transcriptionally induced by brassinosteroids are charcterized in this study. (HERCULES1)
      Title: Three related receptor-like kinases are required for optimal cell elongation in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_114497.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables transmembrane receptor protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within brassinosteroid mediated signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in pollen tube guidance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in pollen tube reception IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within post-embryonic development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of unidimensional cell growth IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within response to brassinosteroid IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within unidimensional cell growth IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in filiform apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    hercules receptor kinase 1
    NP_190214.1
    • hercules receptor kinase 1 (HERK1); FUNCTIONS IN: protein kinase activity, kinase activity; INVOLVED IN: brassinosteroid mediated signaling pathway, post-embryonic development, response to brassinosteroid stimulus, unidimensional cell growth, regulation of unidimensional cell growth; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: Protein kinase superfamily protein (TAIR:AT5G59700.1); Has 116300 Blast hits to 115060 proteins in 4658 species: Archae - 101; Bacteria - 13233; Metazoa - 43205; Fungi - 9848; Plants - 32844; Viruses - 378; Other Eukaryotes - 16691 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      17012500..17015885
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_114497.4 → NP_190214.1  hercules receptor kinase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190214.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LX66, Q9SNA7
      UniProtKB/TrEMBL
      A0A5S9XJ34, A0A654FEL6
      Conserved Domains (2) summary
      cd14066
      Location:491 → 756
      STKc_IRAK; Catalytic domain of the Serine/Threonine kinases, Interleukin-1 Receptor Associated Kinases and related STKs
      pfam12819
      Location:33 → 380
      Malectin_like; Carbohydrate-binding protein of the ER
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LX66.1

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