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    FKBP15-2 FK506- and rapamycin-binding protein 15 kD-2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834915, updated on 18-Sep-2024

    Summary

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    Official Symbol
    FKBP15-2
    Official Full Name
    FK506- and rapamycin-binding protein 15 kD-2
    Primary source
    TAIR:AT5G48580
    Locus tag
    AT5G48580
    See related
    Araport:AT5G48580
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    FK506- and rapamycin-binding protein 15 kD-2; IMMUNOPHILIN; K15N18.5; K15N18_5
    Summary
    immunophilin (FKBP15-2)
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    Genomic context

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    See FKBP15-2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    7
    Sequence:
    Chromosome: 5; NC_003076.8 (19695767..19698712, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene FKBP-type peptidyl-prolyl cis-trans isomerase family protein Neighboring gene mediator of RNA polymerase II transcription subunit-like protein, putative (DUF1216) Neighboring gene phosphoserine aminotransferase, putative (DUF760) Neighboring gene Defensin-like (DEFL) family protein Neighboring gene structural maintenance of chromosome 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Phytophthora capsici RXLR Effector Targets and Inhibits a Plant PPIase to Suppress Endoplasmic Reticulum-Mediated Immunity. Fan G, et al. Mol Plant, 2018 Aug 6. PMID 29864524
    2. The vegetative vacuole proteome of Arabidopsis thaliana reveals predicted and unexpected proteins. Carter C, et al. Plant Cell, 2004 Dec. PMID 15539469, Free PMC Article
    3. Isolation and proteomic characterization of the Arabidopsis Golgi defines functional and novel components involved in plant cell wall biosynthesis. Parsons HT, et al. Plant Physiol, 2012 May. PMID 22430844, Free PMC Article
    4. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article
    5. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_124234.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables peptidyl-prolyl cis-trans isomerase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chaperone-mediated protein folding IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to endoplasmic reticulum stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to fungus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to fungus IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in endoplasmic reticulum HDA PubMed 
    colocalizes_with endoplasmic reticulum cisternal network IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    colocalizes_with haustorium IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plant-type vacuole HDA PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    FK506- and rapamycin-binding protein 15 kD-2
    NP_199669.1
    • FK506- and rapamycin-binding protein 15 kD-2 (FKBP15-2); FUNCTIONS IN: FK506 binding, peptidyl-prolyl cis-trans isomerase activity; INVOLVED IN: protein folding; LOCATED IN: chloroplast thylakoid lumen, vacuole; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Peptidyl-prolyl cis-trans isomerase, FKBP-type (InterPro:IPR001179); BEST Arabidopsis thaliana protein match is: FK506-binding protein 15 kD-1 (TAIR:AT3G25220.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      19695767..19698712 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124234.4 → NP_199669.1  FK506- and rapamycin-binding protein 15 kD-2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199669.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q38936, Q9FJL2
      UniProtKB/TrEMBL
      A0A178UPA7, A0A5S9YC71
      Conserved Domains (1) summary
      pfam00254
      Location:45 → 137
      FKBP_C; FKBP-type peptidyl-prolyl cis-trans isomerase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q38936.2

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