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    ECT3 evolutionarily conserved C-terminal region 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836223, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ECT3
    Official Full Name
    evolutionarily conserved C-terminal region 3
    Primary source
    TAIR:AT5G61020
    Locus tag
    AT5G61020
    See related
    Araport:AT5G61020
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    evolutionarily conserved C-terminal region 3; MAF19.3; MAF19_3
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    Genomic context

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    See ECT3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    7
    Sequence:
    Chromosome: 5; NC_003076.8 (24556994..24559936, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Nuclear transport factor 2 (NTF2) family protein with RNA binding (RRM-RBD-RNP motifs) domain-containing protein Neighboring gene DEA(D/H)-box RNA helicase family protein Neighboring gene Replication factor-A protein 1-like protein Neighboring gene exocyst subunit exo70 family protein E2 Neighboring gene glycine-rich RNA-binding protein 3 Neighboring gene uncharacterized protein Neighboring gene histone deacetylase-related / HD-like protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The YTHDF proteins ECT2 and ECT3 bind largely overlapping target sets and influence target mRNA abundance, not alternative polyadenylation. Arribas-Hernández L, et al. Elife, 2021 Sep 30. PMID 34591013, Free PMC Article
    2. Plant YTHDF proteins are direct effectors of antiviral immunity against an N6-methyladenosine-containing RNA virus. Martínez-Pérez M, et al. EMBO J, 2023 Sep 18. PMID 37431920, Free PMC Article
    3. Recurrent requirement for the m(6)A-ECT2/ECT3/ECT4 axis in the control of cell proliferation during plant organogenesis. Arribas-Hernández L, et al. Development, 2020 Jul 24. PMID 32611605, Free PMC Article
    4. m(6)A readers ECT2/ECT3/ECT4 enhance mRNA stability through direct recruitment of the poly(A) binding proteins in Arabidopsis. Song P, et al. Genome Biol, 2023 Apr 30. PMID 37122016, Free PMC Article
    5. Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism. Ito J, et al. J Proteome Res, 2011 Apr 1. PMID 21166475

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. m[6]A readers ECT2/ECT3/ECT4 enhance mRNA stability through direct recruitment of the poly(A) binding proteins in Arabidopsis.
      Title: m(6)A readers ECT2/ECT3/ECT4 enhance mRNA stability through direct recruitment of the poly(A) binding proteins in Arabidopsis.
    2. The YTHDF proteins ECT2 and ECT3 bind largely overlapping target sets and influence target mRNA abundance, not alternative polyadenylation.
      Title: The YTHDF proteins ECT2 and ECT3 bind largely overlapping target sets and influence target mRNA abundance, not alternative polyadenylation.
    3. Recurrent requirement for the m(6)A-ECT2/ECT3/ECT4 axis in the control of cell proliferation during plant organogenesis.
      Title: Recurrent requirement for the m(6)A-ECT2/ECT3/ECT4 axis in the control of cell proliferation during plant organogenesis.
    Submit: New GeneRIF Correction

    General gene information

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    NM_125495.2
    NM_180905.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mRNA stabilization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in response to abscisic acid IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in response to virus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    NOT located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    evolutionarily conserved C-terminal region 3
    NP_568932.2
    • evolutionarily conserved C-terminal region 3 (ECT3); CONTAINS InterPro DOMAIN/s: YTH domain (InterPro:IPR007275); BEST Arabidopsis thaliana protein match is: evolutionarily conserved C-terminal region 2 (TAIR:AT3G13460.1); Has 1114 Blast hits to 1097 proteins in 185 species: Archae - 0; Bacteria - 6; Metazoa - 492; Fungi - 144; Plants - 353; Viruses - 0; Other Eukaryotes - 119 (source: NCBI BLink).
    NP_851236.1
    • evolutionarily conserved C-terminal region 3 (ECT3); CONTAINS InterPro DOMAIN/s: YTH domain (InterPro:IPR007275); BEST Arabidopsis thaliana protein match is: evolutionarily conserved C-terminal region 2 (TAIR:AT3G13460.4); Has 1118 Blast hits to 1101 proteins in 185 species: Archae - 0; Bacteria - 4; Metazoa - 492; Fungi - 150; Plants - 353; Viruses - 0; Other Eukaryotes - 119 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      24556994..24559936 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180905.3 → NP_851236.1  evolutionarily conserved C-terminal region 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851236.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4K1Z0, Q93ZP1, Q9FNR2
      UniProtKB/TrEMBL
      A0A178UM32, A0A7S8F255
      Conserved Domains (1) summary
      pfam04146
      Location:261 → 399
      YTH; YT521-B-like domain

    2. NM_125495.2 → NP_568932.2  evolutionarily conserved C-terminal region 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568932.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UNW2, A0A7S8F255
      Conserved Domains (1) summary
      pfam04146
      Location:259 → 397
      YTH; YT521-B-like domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4K1Z0.1

    Gene LinkOut

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