U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    THO7 Tho complex subunit 7/Mft1p [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831542, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    THO7
    Official Full Name
    Tho complex subunit 7/Mft1p
    Primary source
    TAIR:AT5G16790
    Locus tag
    AT5G16790
    See related
    Araport:AT5G16790
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtTHO7; F5E19.130; F5E19_130
    Summary
    Encodes a component of the putative Arabidopsis THO/TREX complex: THO1 or HPR1 (At5g09860), THO2 (At1g24706), THO3 or TEX1 (At5g56130), THO5 (At5g42920, At1g45233), THO6 (At2g19430), and THO7 (At5g16790, At3g02950). THO/TREX complexes in animals have been implicated in the transport of mRNA precursors. Mutants of THO3/TEX1, THO1, THO6 accumulate reduced amount of small interfering (si)RNA, suggesting a role of the putative Arabidopsis THO/TREX in siRNA biosynthesis.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See THO7 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Sequence:
    Chromosome: 5; NC_003076.8 (5522417..5524011, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Inositol 1,3,4-trisphosphate 5/6-kinase family protein Neighboring gene myb domain protein 9 Neighboring gene SART-1 family Neighboring gene Acyl-CoA N-acyltransferases (NAT) superfamily protein Neighboring gene Protein kinase superfamily protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Putative Arabidopsis THO/TREX mRNA export complex is involved in transgene and endogenous siRNA biosynthesis. Yelina NE, et al. Proc Natl Acad Sci U S A, 2010 Aug 3. PMID 20634427, Free PMC Article
    2. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_001343466.1
    NM_121685.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    part_of THO complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of THO complex part of transcription export complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Tho complex subunit 7/Mft1p
    NP_568339.1
    • THO7; CONTAINS InterPro DOMAIN/s: Tho complex subunit 7 (InterPro:IPR018018), Tho complex subunit 7/Mft1p (InterPro:IPR008501); BEST Arabidopsis thaliana protein match is: Tho complex subunit 7/Mft1p (TAIR:AT3G02950.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      5522417..5524011 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121685.5 → NP_568339.1  Tho complex subunit 7/Mft1p [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568339.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0MFG2, Q8LDS5, Q9LFD9
      UniProtKB/TrEMBL
      A0A178UEM6, A0A7G2FD40
      Conserved Domains (1) summary
      pfam05615
      Location:28 → 165
      THOC7; Tho complex subunit 7

    2. NM_001343466.1 → NP_001331398.1  Tho complex subunit 7/Mft1p [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0MFG2, Q8LDS5, Q9LFD9
      UniProtKB/TrEMBL
      A0A178UEM6, A0A7G2FD40
      Conserved Domains (1) summary
      pfam05615
      Location:28 → 165
      THOC7; Tho complex subunit 7
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8LDS5.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools