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    zf30C zinc finger protein 30C [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34292, updated on 9-Dec-2024

    Summary

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    Official Symbol
    zf30Cprovided by FlyBase
    Official Full Name
    zinc finger protein 30Cprovided by FlyBase
    Primary source
    FLYBASE:FBgn0270924
    Locus tag
    Dmel_CG3998
    See related
    AllianceGenome:FB:FBgn0270924
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:Liang-1.52; C282; CG3998; clone 1.52; Dmel\CG3998; l(2)k02506; zf30c; Zf30c; Zf30C; Zn30C
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including antennal primordium; cuboidal/columnar epithelium; ganglia; head epidermis primordium; and mesoderm. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See zf30C in Genome Data Viewer
    Location:
    30C7-30C7; 2-36 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (9758342..9762375)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (9758342..9762375)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR46529 Neighboring gene Cytochrome P450 4e3 Neighboring gene TBP-associated factor 11 Neighboring gene uninitiated

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A methionine aminopeptidase and putative regulator of translation initiation is required for cell growth and patterning in Drosophila. Cutforth T, et al. Mech Dev, 1999 Apr. PMID 10354468
    2. AT-hook motifs identified in a wide variety of DNA-binding proteins. Aravind L, et al. Nucleic Acids Res, 1998 Oct 1. PMID 9742243, Free PMC Article
    3. A gain-of-function screen identifying genes required for growth and pattern formation of the Drosophila melanogaster wing. Cruz C, et al. Genetics, 2009 Nov. PMID 19737745, Free PMC Article
    4. Developmental Robustness: The Haltere Case in Drosophila. Giraud G, et al. Front Cell Dev Biol, 2021. PMID 34368162, Free PMC Article
    5. Physical and genetic interactions link hox function with diverse transcription factors and cell signaling proteins. Bondos SE, et al. Mol Cell Proteomics, 2006 May. PMID 16455680

    See all (50) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. study presents a preliminary characterization of a gene, CG3998, the function of which is required for the development of the L5 longitudinal vein
      Title: A gain-of-function screen identifying genes required for growth and pattern formation of the Drosophila melanogaster wing.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    zinc finger protein 30C
    Names
    CG3998-PA
    zf30C-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      9758342..9762375
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_057953.5 → NP_477301.1  zinc finger protein 30C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_477301.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O44122, Q9VL91
      Related
      FBpp0079461
      Conserved Domains (3) summary
      COG5048
      Location:523 → 672
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:603 → 624
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:511 → 532
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O44122 O44122
    Q9VL91 Q9VL91

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