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    CG34396 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37398, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG34396provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0085425
    Locus tag
    Dmel_CG34396
    See related
    AllianceGenome:FB:FBgn0085425
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0109301.1; anon-WO0109301.16; anon-WO0109301.17; CG15654; CG15655; Dmel\CG34396
    Old locus tag
    CG15654; CG15655; Dmel_CG15654; Dmel_CG15655
    Summary
    Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in adult head and spermatozoon. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG34396 in Genome Data Viewer
    Location:
    57B20-57B20; 2-92 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (21092222..21101453)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16979727..16988958)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR44704 Neighboring gene uncharacterized protein Neighboring gene Trehalase Neighboring gene Rabaptin-5 Neighboring gene Gar1 ribonucleoprotein Neighboring gene king tubby Neighboring gene uncharacterized protein Neighboring gene Transmembrane O-mannosyltransferase targeting cadherins 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel Drosophila two-pore domain K channels: rescue of channel function by heteromeric assembly. Döring F, et al. Eur J Neurosci, 2006 Oct. PMID 17074048
    2. Rabaptin-5 and Rabex-5 are neoplastic tumour suppressor genes that interact to modulate Rab5 dynamics in Drosophila melanogaster. Thomas C, et al. Dev Biol, 2014 Jan 1. PMID 24104056, Free PMC Article
    3. Operation of a homeostatic sleep switch. Pimentel D, et al. Nature, 2016 Aug 18. PMID 27487216, Free PMC Article
    4. The Drosophila Small Conductance Calcium-Activated Potassium Channel Negatively Regulates Nociception. Walcott KCE, et al. Cell Rep, 2018 Sep 18. PMID 30231996, Free PMC Article
    5. Regulation of Metabolism by an Ensemble of Different Ion Channel Types: Excitation-Secretion Coupling Mechanisms of Adipokinetic Hormone Producing Cells in Drosophila. Perry RJ, et al. Front Physiol, 2020. PMID 33192586, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables outward rectifier potassium channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables potassium channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables potassium ion leak channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in potassium ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in potassium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in potassium ion transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG34396-PC
    CG34396-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      21092222..21101453
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001103922.2 → NP_001097392.1  uncharacterized protein Dmel_CG34396, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097392.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q1WWA9, Q9W2L9
      Conserved Domains (1) summary
      pfam07885
      Location:360 → 436
      Ion_trans_2; Ion channel

    2. NM_137703.3 → NP_611547.2  uncharacterized protein Dmel_CG34396, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611547.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W2L7
      Conserved Domains (2) summary
      pfam07885
      Location:771 → 847
      Ion_trans_2; Ion channel
      cl23720
      Location:135 → 217
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W2L7 Q9W2L7
    Q9W2L9 Q9W2L9

    Gene LinkOut

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