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    witty without maturity [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34145, updated on 9-Dec-2024

    Summary

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    Official Symbol
    wittyprovided by FlyBase
    Official Full Name
    without maturityprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032023
    Locus tag
    Dmel_CG14274
    See related
    AllianceGenome:FB:FBgn0032023
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG14274; Dmel\CG14274
    Summary
    Predicted to be involved in regulation of cholinergic synaptic transmission and sleep. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See witty in Genome Data Viewer
    Location:
    29A5-29B1; 2-31 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (8338287..8342056)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (8338287..8342056)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene stratum Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45371 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dichotomous cis-regulatory motifs mediate the maturation of the neuromuscular junction by retrograde BMP signaling. Vuilleumier R, et al. Nucleic Acids Res, 2022 Sep 23. PMID 36029115, Free PMC Article
    2. Crooked, coiled and crimpled are three Ly6-like proteins required for proper localization of septate junction components. Nilton A, et al. Development, 2010 Jul. PMID 20570942, Free PMC Article
    3. boudin is required for septate junction organisation in Drosophila and codes for a diffusible protein of the Ly6 superfamily. Hijazi A, et al. Development, 2009 Jul. PMID 19502482
    4. Genetic basis and repeatability for desiccation resistance in Drosophila melanogaster (Diptera: Drosophilidae). Fanara JJ, et al. Genetica, 2024 Feb. PMID 38102503
    5. A single-cell transcriptomic atlas of complete insect nervous systems across multiple life stages. Corrales M, et al. Neural Dev, 2022 Aug 24. PMID 36002881, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in positive regulation of voltage-gated potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of synaptic transmission, cholinergic IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sleep IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of synapse maturation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    without maturity
    Names
    CG14274-PA
    witty-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      8338287..8342056
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135368.3 → NP_609212.2  without maturity [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609212.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V4N0, Q9VLP0
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VLP0 Q9VLP0

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