CSN3 COP9 signalosome subunit 3 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CSN3provided by FlyBase
Official Full Name: COP9 signalosome subunit 3provided by FlyBase
Primary source: FLYBASE:FBgn0027055
Locus tag: Dmel_CG18332
See related: AllianceGenome:FB:FBgn0027055
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG18332; CH3; csn3; Csn3; Dch3; DCH3; dCSN3; Dmel\CG18332; FBgn0027055
Summary: Involved in several processes, including female germ-line stem cell population maintenance; germarium-derived cystoblast division; and male germ-line cyst encapsulation. Predicted to be part of COP9 signalosome. Is expressed in central brain primordium; embryonic brain; larval ventral nerve cord; organism; and ventral nerve cord primordium. Orthologous to human COPS3 (COP9 signalosome subunit 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (20839096..20841576, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (20832196..20834676, complement)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Process	Evidence Code	Pubs
involved_in female germ-line stem cell population maintenance	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in germ cell development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in germarium-derived cystoblast division	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in male germ-line cyst encapsulation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein deneddylation	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein stabilization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in ubiquitin-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of COP9 signalosome	IBA Inferred from Biological aspect of Ancestor more info
part_of COP9 signalosome	ISS Inferred from Sequence or Structural Similarity more info	PubMed