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    Rnd3 Rho family GTPase 3 [ Mus musculus (house mouse) ]

    Gene ID: 74194, updated on 27-Dec-2024

    Summary

    Official Symbol
    Rnd3provided by MGI
    Official Full Name
    Rho family GTPase 3provided by MGI
    Primary source
    MGI:MGI:1921444
    See related
    Ensembl:ENSMUSG00000017144 AllianceGenome:MGI:1921444
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Arhe; Rhoe; 2610017M01Rik
    Summary
    Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in actin filament organization; regulation of actin cytoskeleton organization; and signal transduction. Predicted to be located in Golgi membrane. Predicted to be active in cytosol and plasma membrane. Is expressed in several structures, including cardiovascular system; central nervous system; genitourinary system; liver; and retina. Orthologous to human RND3 (Rho family GTPase 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in CNS E11.5 (RPKM 46.9), whole brain E14.5 (RPKM 28.6) and 11 other tissues See more
    Orthologs
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    Genomic context

    See Rnd3 in Genome Data Viewer
    Location:
    2 C1.1; 2 29.63 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (51020451..51039123, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (51130439..51149111, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 39811 Neighboring gene heat shock protein 90 alpha (cytosolic), class B member 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_04455 Neighboring gene STARR-seq mESC enhancer starr_04456 Neighboring gene STARR-seq mESC enhancer starr_04457 Neighboring gene STARR-seq mESC enhancer starr_04458 Neighboring gene STARR-seq mESC enhancer starr_04461 Neighboring gene predicted gene, 32360 Neighboring gene STARR-seq mESC enhancer starr_04462 Neighboring gene STARR-seq mESC enhancer starr_04463 Neighboring gene STARR-seq mESC enhancer starr_04464 Neighboring gene STARR-seq mESC enhancer starr_04465 Neighboring gene pyrophosphatase (inorganic) 1 pseudogene Neighboring gene predicted gene 13497

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTP binding  
    enables GTP binding  
    enables GTPase activity  
    enables GTPase activity  
    enables protein binding PubMed 
    enables protein kinase binding  
    Process Evidence Code Pubs
    involved_in actin filament organization  
    involved_in regulation of actin cytoskeleton organization  
    involved_in signal transduction  
    involved_in small GTPase-mediated signal transduction  
    Component Evidence Code Pubs
    located_in Golgi membrane  
    is_active_in cytosol  
    is_active_in plasma membrane  

    General protein information

    Preferred Names
    rho-related GTP-binding protein RhoE
    Names
    ras homolog gene family, member E

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028810.2NP_083086.1  rho-related GTP-binding protein RhoE

      See identical proteins and their annotated locations for NP_083086.1

      Status: PROVISIONAL

      Source sequence(s)
      AL844893
      Consensus CDS
      CCDS16028.1
      UniProtKB/Swiss-Prot
      P61588, Q6ZWS2
      Related
      ENSMUSP00000017288.3, ENSMUST00000017288.9
      Conserved Domains (1) summary
      cd04172
      Location:19200
      Rnd3_RhoE_Rho8; Rnd3/RhoE/Rho8 GTPases

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      51020451..51039123 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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