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    Ablim2 actin-binding LIM protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 231148, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ablim2provided by MGI
    Official Full Name
    actin-binding LIM protein 2provided by MGI
    Primary source
    MGI:MGI:2385758
    See related
    Ensembl:ENSMUSG00000029095 AllianceGenome:MGI:2385758
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C230091L11
    Summary
    Predicted to enable actin filament binding activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in myofibril. Is expressed in several structures, including brain; diaphragm; early conceptus; oocyte; and skeletal muscle. Orthologous to human ABLIM2 (actin binding LIM protein family member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in cortex adult (RPKM 21.7), frontal lobe adult (RPKM 17.1) and 17 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Ablim2 in Genome Data Viewer
    Location:
    5 B3; 5 18.75 cM
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (35915200..36042323)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (35757855..35884979)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_12860 Neighboring gene HtrA serine peptidase 3 Neighboring gene STARR-positive B cell enhancer ABC_E8820 Neighboring gene SH3 domain and tetratricopeptide repeats 1 Neighboring gene predicted gene, 31888 Neighboring gene STARR-positive B cell enhancer ABC_E8050 Neighboring gene H2A histone family, pseudogene 1 Neighboring gene actin filament associated protein 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:36316611-36316857 Neighboring gene STARR-positive B cell enhancer mm9_chr5:36376513-36376814 Neighboring gene sortilin-related VPS10 domain containing receptor 2 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:36431991-36432296 Neighboring gene predicted gene, 52811

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genomic organisation and tissue specific expression of ABLIM2 gene in human, mouse and rat. Klimov E, et al. Biochim Biophys Acta, 2005 Jul 25. PMID 16005990
    2. Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin. Barrientos T, et al. J Biol Chem, 2007 Mar 16. PMID 17194709
    3. Vti1b promotes TRPV1 sensitization during inflammatory pain. Sondermann JR, et al. Pain, 2019 Feb. PMID 30335684
    4. Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca(2+)/CaM) and CaM Kinase II (CaMKII) Binding Partner. Evans PR, et al. J Proteome Res, 2018 Apr 6. PMID 29518331, Free PMC Article
    5. Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Trinidad JC, et al. Mol Cell Proteomics, 2006 May. PMID 16452087

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ABLIM-2 and -3 associate with STARS and directly bind F-actin
      Title: Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin.
    2. The highest expression of both isoforms was observed in rat brain and eye and in mouse embryos. ABLIM2 protein was necessary for the normal functioning of neurons.
      Title: Genomic organisation and tissue specific expression of ABLIM2 gene in human, mouse and rat.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in lamellipodium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in actin cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    located_in myofibril IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    actin-binding LIM protein 2
    Names
    abLIM-2
    actin-binding LIM protein family member 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001177696.1 → NP_001171167.1  actin-binding LIM protein 2 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AC141898
      Consensus CDS
      CCDS51473.1
      UniProtKB/TrEMBL
      E9Q4K0, Q19VH2
      Related
      ENSMUSP00000123525.2, ENSMUST00000129347.8
      Conserved Domains (6) summary
      cd09327
      Location:24 → 75
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:80 → 135
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:153 → 204
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:212 → 267
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:630 → 664
      VHP; Villin headpiece domain
      pfam16182
      Location:296 → 628
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    2. NM_001177697.1 → NP_001171168.1  actin-binding LIM protein 2 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks three alternate exons and includes an alternate exon, compared to variant 1. The resulting isoform (2) lacks two internal segments and includes an additional internal segment, compared to isoform 1.
      Source sequence(s)
      AC141898, AK046243, AK046879
      Consensus CDS
      CCDS51475.1
      UniProtKB/TrEMBL
      Q3U409
      Related
      ENSMUSP00000109844.3, ENSMUST00000114206.9
      Conserved Domains (6) summary
      cd09327
      Location:24 → 75
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:80 → 135
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:153 → 204
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:212 → 267
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:583 → 617
      VHP; Villin headpiece domain
      pfam16182
      Location:277 → 581
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    3. NM_001177698.1 → NP_001171169.1  actin-binding LIM protein 2 isoform 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks three alternate exons, compared to variant 1. The resulting isoform (4) lacks two internal segments, compared to isoform 1.
      Source sequence(s)
      AC141898
      Consensus CDS
      CCDS51474.1
      UniProtKB/TrEMBL
      E9Q0W6, Q3U409
      Related
      ENSMUSP00000098838.4, ENSMUST00000101280.10
      Conserved Domains (6) summary
      cd09327
      Location:24 → 75
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:80 → 135
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:153 → 204
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:212 → 267
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:573 → 607
      VHP; Villin headpiece domain
      pfam16182
      Location:296 → 571
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    4. NM_001177699.1 → NP_001171170.1  actin-binding LIM protein 2 isoform 5

      See identical proteins and their annotated locations for NP_001171170.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) lacks three alternate exons, compared to variant 1. The resulting isoform (5) lacks two internal segments, compared to isoform 1.
      Source sequence(s)
      AC141898, AY274116
      Consensus CDS
      CCDS51476.1
      UniProtKB/TrEMBL
      Q3U409
      Related
      ENSMUSP00000109842.2, ENSMUST00000114204.8
      Conserved Domains (6) summary
      cd09327
      Location:24 → 75
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:80 → 135
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:153 → 204
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:212 → 267
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:572 → 606
      VHP; Villin headpiece domain
      pfam16182
      Location:277 → 570
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    5. NM_001177700.1 → NP_001171171.1  actin-binding LIM protein 2 isoform 6

      See identical proteins and their annotated locations for NP_001171171.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) lacks four alternate exons, compared to variant 1. The resulting isoform (6) lacks three internal segments, compared to isoform 1.
      Source sequence(s)
      AC141898
      Consensus CDS
      CCDS51477.1
      UniProtKB/TrEMBL
      Q3U409
      Related
      ENSMUSP00000109843.2, ENSMUST00000114205.8
      Conserved Domains (6) summary
      cd09327
      Location:24 → 75
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:80 → 135
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:153 → 204
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:212 → 267
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:539 → 573
      VHP; Villin headpiece domain
      pfam16182
      Location:277 → 537
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    6. NM_177678.7 → NP_808346.3  actin-binding LIM protein 2 isoform 3

      See identical proteins and their annotated locations for NP_808346.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks two alternate exons, compared to variant 1. The resulting isoform (3) lacks two internal segments, compared to isoform 1.
      Source sequence(s)
      AC141898, AK046243, AK046879
      Consensus CDS
      CCDS19235.1
      UniProtKB/Swiss-Prot
      B2RUF8, Q6H8P8, Q80WK6, Q8BL65, Q8BUT1, Q8BXI7
      UniProtKB/TrEMBL
      Q19VH2
      Related
      ENSMUSP00000050571.6, ENSMUST00000054598.12
      Conserved Domains (6) summary
      cd09327
      Location:24 → 75
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:80 → 135
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:153 → 204
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:212 → 267
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:578 → 612
      VHP; Villin headpiece domain
      pfam16182
      Location:277 → 576
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      35915200..36042323
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006503906.2 → XP_006503969.1  actin-binding LIM protein 2 isoform X2

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (6) summary
      cd09327
      Location:24 → 75
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:80 → 135
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:153 → 204
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:212 → 267
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:680 → 714
      VHP; Villin headpiece domain
      pfam16182
      Location:295 → 678
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    2. XM_006503912.2 → XP_006503975.1  actin-binding LIM protein 2 isoform X13

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (6) summary
      cd09327
      Location:24 → 75
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:80 → 135
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:153 → 204
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:212 → 267
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:640 → 674
      VHP; Villin headpiece domain
      pfam16182
      Location:295 → 638
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    3. XM_030254381.2 → XP_030110241.1  actin-binding LIM protein 2 isoform X22

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (6) summary
      cd09327
      Location:24 → 75
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:80 → 135
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:153 → 204
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:212 → 267
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:607 → 641
      VHP; Villin headpiece domain
      pfam16182
      Location:295 → 605
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    4. XM_006503907.2 → XP_006503970.1  actin-binding LIM protein 2 isoform X4

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (6) summary
      cd09327
      Location:24 → 75
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:80 → 135
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:153 → 204
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:212 → 267
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:669 → 703
      VHP; Villin headpiece domain
      pfam16182
      Location:295 → 667
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    5. XM_006503908.2 → XP_006503971.1  actin-binding LIM protein 2 isoform X6

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (6) summary
      cd09327
      Location:24 → 75
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:80 → 135
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:153 → 204
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:212 → 267
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:661 → 695
      VHP; Villin headpiece domain
      pfam16182
      Location:276 → 659
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    6. XM_036165035.1 → XP_036020928.1  actin-binding LIM protein 2 isoform X18

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (6) summary
      cd09327
      Location:24 → 75
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:80 → 135
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:153 → 204
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:212 → 267
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:621 → 655
      VHP; Villin headpiece domain
      pfam16182
      Location:276 → 620
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    7. XM_036165042.1 → XP_036020935.1  actin-binding LIM protein 2 isoform X28

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (6) summary
      cd09327
      Location:24 → 75
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:80 → 135
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:153 → 204
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:212 → 267
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:588 → 622
      VHP; Villin headpiece domain
      pfam16182
      Location:276 → 587
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    8. XM_006503909.2 → XP_006503972.1  actin-binding LIM protein 2 isoform X9

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (6) summary
      cd09327
      Location:24 → 75
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:80 → 135
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:153 → 204
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:212 → 267
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:650 → 684
      VHP; Villin headpiece domain
      pfam16182
      Location:276 → 648
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    9. XM_030254383.2 → XP_030110243.1  actin-binding LIM protein 2 isoform X32

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (6) summary
      cd09327
      Location:24 → 75
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:80 → 135
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:153 → 204
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:212 → 267
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:559 → 593
      VHP; Villin headpiece domain
      pfam16182
      Location:276 → 557
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    10. XM_006503922.2 → XP_006503985.1  actin-binding LIM protein 2 isoform X33

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (6) summary
      smart00153
      Location:525 → 560
      VHP; Villin headpiece domain
      cd09327
      Location:24 → 75
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:80 → 135
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:153 → 204
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:212 → 267
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam16182
      Location:276 → 523
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    11. XM_006503916.2 → XP_006503979.1  actin-binding LIM protein 2 isoform X21

      UniProtKB/TrEMBL
      Q19VH2
      Related
      ENSMUSP00000109848.3, ENSMUST00000114210.9
      Conserved Domains (6) summary
      cd09327
      Location:24 → 75
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:80 → 135
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:153 → 204
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:212 → 267
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:610 → 644
      VHP; Villin headpiece domain
      pfam16182
      Location:276 → 608
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    12. XM_030254382.2 → XP_030110242.1  actin-binding LIM protein 2 isoform X27

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (6) summary
      cd09327
      Location:24 → 75
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:80 → 135
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:153 → 204
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:212 → 267
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:592 → 626
      VHP; Villin headpiece domain
      pfam16182
      Location:276 → 590
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    13. XM_036165027.1 → XP_036020920.1  actin-binding LIM protein 2 isoform X8

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (6) summary
      cd09327
      Location:29 → 80
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:85 → 140
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:158 → 209
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:217 → 272
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:652 → 686
      VHP; Villin headpiece domain
      pfam16182
      Location:300 → 651
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    14. XM_036165033.1 → XP_036020926.1  actin-binding LIM protein 2 isoform X16

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (5) summary
      cd09327
      Location:29 → 80
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:85 → 140
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:158 → 209
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:217 → 272
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam16182
      Location:300 → 657
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    15. XM_036165039.1 → XP_036020932.1  actin-binding LIM protein 2 isoform X24

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (5) summary
      cd09327
      Location:29 → 80
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:85 → 140
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:158 → 209
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:217 → 272
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam16182
      Location:300 → 632
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    16. XM_036165043.1 → XP_036020936.1  actin-binding LIM protein 2 isoform X29

      UniProtKB/TrEMBL
      Q3U409
      Conserved Domains (5) summary
      cd09327
      Location:29 → 80
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:85 → 140
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:158 → 209
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:217 → 272
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam16182
      Location:300 → 586
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    17. XM_036165023.1 → XP_036020916.1  actin-binding LIM protein 2 isoform X1

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (6) summary
      cd09327
      Location:29 → 80
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:85 → 140
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:158 → 209
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:217 → 272
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:685 → 719
      VHP; Villin headpiece domain
      pfam16182
      Location:300 → 684
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    18. XM_036165030.1 → XP_036020923.1  actin-binding LIM protein 2 isoform X12

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (6) summary
      cd09327
      Location:29 → 80
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:85 → 140
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:158 → 209
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:217 → 272
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:641 → 675
      VHP; Villin headpiece domain
      pfam16182
      Location:300 → 640
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    19. XM_036165037.1 → XP_036020930.1  actin-binding LIM protein 2 isoform X20

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (6) summary
      cd09327
      Location:29 → 80
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:85 → 140
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:158 → 209
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:217 → 272
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:612 → 646
      VHP; Villin headpiece domain
      pfam16182
      Location:300 → 611
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    20. XM_036165034.1 → XP_036020927.1  actin-binding LIM protein 2 isoform X17

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (6) summary
      cd09327
      Location:29 → 80
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:85 → 140
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:158 → 209
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:217 → 272
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:622 → 656
      VHP; Villin headpiece domain
      pfam16182
      Location:281 → 621
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    21. XM_036165025.1 → XP_036020918.1  actin-binding LIM protein 2 isoform X5

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (6) summary
      cd09327
      Location:29 → 80
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:85 → 140
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:158 → 209
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:217 → 272
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:666 → 700
      VHP; Villin headpiece domain
      pfam16182
      Location:281 → 665
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    22. XM_036165028.1 → XP_036020921.1  actin-binding LIM protein 2 isoform X10

      UniProtKB/TrEMBL
      Q3U409
      Conserved Domains (6) summary
      cd09327
      Location:29 → 80
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:85 → 140
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:158 → 209
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:217 → 272
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:646 → 680
      VHP; Villin headpiece domain
      pfam16182
      Location:300 → 645
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    23. XM_036165032.1 → XP_036020925.1  actin-binding LIM protein 2 isoform X15

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (6) summary
      cd09327
      Location:29 → 80
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:85 → 140
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:158 → 209
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:217 → 272
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:627 → 661
      VHP; Villin headpiece domain
      pfam16182
      Location:300 → 626
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    24. XM_036165024.1 → XP_036020917.1  actin-binding LIM protein 2 isoform X3

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (6) summary
      cd09327
      Location:29 → 80
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:85 → 140
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:158 → 209
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:217 → 272
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:674 → 708
      VHP; Villin headpiece domain
      pfam16182
      Location:300 → 673
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    25. XM_036165041.1 → XP_036020934.1  actin-binding LIM protein 2 isoform X26

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (6) summary
      cd09327
      Location:29 → 80
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:85 → 140
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:158 → 209
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:217 → 272
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:593 → 627
      VHP; Villin headpiece domain
      pfam16182
      Location:281 → 592
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    26. XM_036165029.1 → XP_036020922.1  actin-binding LIM protein 2 isoform X11

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (6) summary
      cd09327
      Location:29 → 80
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:85 → 140
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:158 → 209
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:217 → 272
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:645 → 679
      VHP; Villin headpiece domain
      pfam16182
      Location:300 → 644
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    27. XM_036165040.1 → XP_036020933.1  actin-binding LIM protein 2 isoform X25

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (6) summary
      cd09327
      Location:29 → 80
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:85 → 140
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:158 → 209
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:217 → 272
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:601 → 635
      VHP; Villin headpiece domain
      pfam16182
      Location:300 → 600
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    28. XM_036165026.1 → XP_036020919.1  actin-binding LIM protein 2 isoform X7

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (6) summary
      cd09327
      Location:29 → 80
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:85 → 140
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:158 → 209
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:217 → 272
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:655 → 689
      VHP; Villin headpiece domain
      pfam16182
      Location:281 → 654
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    29. XM_036165045.1 → XP_036020938.1  actin-binding LIM protein 2 isoform X31

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (6) summary
      cd09327
      Location:29 → 80
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:85 → 140
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:158 → 209
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:217 → 272
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:582 → 616
      VHP; Villin headpiece domain
      pfam16182
      Location:281 → 581
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    30. XM_036165031.1 → XP_036020924.1  actin-binding LIM protein 2 isoform X14

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (6) summary
      cd09327
      Location:29 → 80
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:85 → 140
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:158 → 209
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:217 → 272
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:634 → 668
      VHP; Villin headpiece domain
      pfam16182
      Location:300 → 633
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    31. XM_036165038.1 → XP_036020931.1  actin-binding LIM protein 2 isoform X23

      UniProtKB/TrEMBL
      Q3U409
      Conserved Domains (6) summary
      cd09327
      Location:29 → 80
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:85 → 140
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:158 → 209
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:217 → 272
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:606 → 640
      VHP; Villin headpiece domain
      pfam16182
      Location:300 → 605
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    32. XM_036165044.1 → XP_036020937.1  actin-binding LIM protein 2 isoform X30

      UniProtKB/TrEMBL
      Q3U409
      Conserved Domains (6) summary
      cd09327
      Location:29 → 80
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:85 → 140
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:158 → 209
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:217 → 272
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:587 → 621
      VHP; Villin headpiece domain
      pfam16182
      Location:281 → 586
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    33. XM_036165036.1 → XP_036020929.1  actin-binding LIM protein 2 isoform X19

      UniProtKB/TrEMBL
      Q19VH2
      Conserved Domains (6) summary
      cd09327
      Location:29 → 80
      LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
      cd09328
      Location:85 → 140
      LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
      cd09329
      Location:158 → 209
      LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
      cd09330
      Location:217 → 272
      LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
      pfam02209
      Location:615 → 649
      VHP; Villin headpiece domain
      pfam16182
      Location:281 → 614
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    34. XM_006503925.4 → XP_006503988.1  actin-binding LIM protein 2 isoform X34

      Conserved Domains (3) summary
      cl02475
      Location:1 → 24
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
      pfam02209
      Location:437 → 471
      VHP; Villin headpiece domain
      pfam16182
      Location:52 → 435
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    35. XM_036165049.1 → XP_036020942.1  actin-binding LIM protein 2 isoform X40

      UniProtKB/TrEMBL
      D3Z0Y4
      Conserved Domains (3) summary
      pfam02209
      Location:364 → 398
      VHP; Villin headpiece domain
      pfam16182
      Location:52 → 363
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
      cl02475
      Location:1 → 24
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    36. XM_006503926.4 → XP_006503989.1  actin-binding LIM protein 2 isoform X35

      Conserved Domains (3) summary
      smart00153
      Location:418 → 453
      VHP; Villin headpiece domain
      cl02475
      Location:1 → 24
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
      pfam16182
      Location:33 → 416
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    37. XM_036165051.1 → XP_036020944.1  actin-binding LIM protein 2 isoform X42

      UniProtKB/TrEMBL
      D3Z0Y4
      Related
      ENSMUSP00000109841.2, ENSMUST00000114203.8
      Conserved Domains (3) summary
      smart00153
      Location:345 → 380
      VHP; Villin headpiece domain
      pfam16182
      Location:33 → 344
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
      cl02475
      Location:1 → 24
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    38. XM_036165046.1 → XP_036020939.1  actin-binding LIM protein 2 isoform X36

      UniProtKB/TrEMBL
      D3Z0Y4
      Conserved Domains (3) summary
      pfam02209
      Location:397 → 431
      VHP; Villin headpiece domain
      pfam16182
      Location:52 → 396
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
      cl02475
      Location:1 → 24
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    39. XM_036165048.1 → XP_036020941.1  actin-binding LIM protein 2 isoform X38

      UniProtKB/TrEMBL
      D3Z0Y4
      Conserved Domains (3) summary
      pfam02209
      Location:378 → 412
      VHP; Villin headpiece domain
      pfam16182
      Location:33 → 377
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
      cl02475
      Location:1 → 24
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    40. XM_030254385.2 → XP_030110245.1  actin-binding LIM protein 2 isoform X43

      UniProtKB/TrEMBL
      D3Z0Y4
      Conserved Domains (3) summary
      smart00153
      Location:334 → 369
      VHP; Villin headpiece domain
      cl02475
      Location:1 → 24
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
      pfam16182
      Location:33 → 332
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    41. XM_036165047.1 → XP_036020940.1  actin-binding LIM protein 2 isoform X37

      Conserved Domains (3) summary
      pfam02209
      Location:386 → 420
      VHP; Villin headpiece domain
      pfam16182
      Location:52 → 385
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
      cl02475
      Location:1 → 24
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    42. XM_036165050.1 → XP_036020943.1  actin-binding LIM protein 2 isoform X41

      UniProtKB/TrEMBL
      D3Z0Y4
      Conserved Domains (3) summary
      pfam02209
      Location:349 → 383
      VHP; Villin headpiece domain
      pfam16182
      Location:33 → 348
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
      cl02475
      Location:1 → 24
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    43. XM_030254384.2 → XP_030110244.1  actin-binding LIM protein 2 isoform X39

      UniProtKB/TrEMBL
      D3Z0Y4
      Conserved Domains (3) summary
      smart00153
      Location:367 → 402
      VHP; Villin headpiece domain
      cl02475
      Location:1 → 24
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
      pfam16182
      Location:33 → 365
      AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

    RNA

    1. XR_004942495.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BL65.1 GenPept UniProtKB/Swiss-Prot:Q8BL65

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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