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    Zfp994 zinc finger protein 994 [ Mus musculus (house mouse) ]

    Gene ID: 240038, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp994provided by MGI
    Official Full Name
    zinc finger protein 994provided by MGI
    Primary source
    MGI:MGI:3643318
    See related
    Ensembl:ENSMUSG00000096433 AllianceGenome:MGI:3643318
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm4944; EG240038
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Zfp994 in Genome Data Viewer
    Location:
    17 A3.3; 17 11.4 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (22416246..22444640, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (22197265..22225659, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_42024 Neighboring gene zinc finger protein 947 Neighboring gene sorting nexin 4 pseudogene Neighboring gene predicted gene, 52309 Neighboring gene STARR-seq mESC enhancer starr_42025 Neighboring gene STARR-positive B cell enhancer ABC_E4195 Neighboring gene STARR-seq mESC enhancer starr_42027 Neighboring gene predicted gene 7072 Neighboring gene STARR-seq mESC enhancer starr_42028 Neighboring gene predicted gene, 53992 Neighboring gene zinc finger protein 944 Neighboring gene STARR-positive B cell enhancer ABC_E5576 Neighboring gene zinc finger protein 758

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC240038

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205095.2 → NP_001192024.1  uncharacterized protein LOC240038 isoform 1

      See identical proteins and their annotated locations for NP_001192024.1

      Status: VALIDATED

      Source sequence(s)
      CT030661
      Consensus CDS
      CCDS57054.1
      UniProtKB/TrEMBL
      J3QM38
      Related
      ENSMUSP00000136105.2, ENSMUST00000179996.3
      Conserved Domains (3) summary
      COG5048
      Location:265 → 661
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:269 → 289
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:13 → 52
      KRAB; KRAB box

    2. NM_001418923.1 → NP_001405852.1  uncharacterized protein LOC240038 isoform 1

      Status: VALIDATED

      Source sequence(s)
      CT030661
      UniProtKB/TrEMBL
      J3QM38

    3. NM_001418925.1 → NP_001405854.1  uncharacterized protein LOC240038 isoform 1

      Status: VALIDATED

      Source sequence(s)
      CT030661
      UniProtKB/TrEMBL
      J3QM38

    4. NM_001418926.1 → NP_001405855.1  uncharacterized protein LOC240038 isoform 1

      Status: VALIDATED

      Source sequence(s)
      CT030661
      UniProtKB/TrEMBL
      J3QM38

    5. NM_001418928.1 → NP_001405857.1  uncharacterized protein LOC240038 isoform 1

      Status: VALIDATED

      Source sequence(s)
      CT030661
      UniProtKB/TrEMBL
      J3QM38

    6. NM_001418931.1 → NP_001405860.1  uncharacterized protein LOC240038 isoform 1

      Status: VALIDATED

      Source sequence(s)
      CT030661
      UniProtKB/TrEMBL
      J3QM38

    7. NM_001418933.1 → NP_001405862.1  uncharacterized protein LOC240038 isoform 1

      Status: VALIDATED

      Source sequence(s)
      CT030661
      UniProtKB/TrEMBL
      J3QM38

    8. NM_001418934.1 → NP_001405863.1  uncharacterized protein LOC240038 isoform 2

      Status: VALIDATED

      Source sequence(s)
      CT030661

    9. NM_001418936.1 → NP_001405865.1  uncharacterized protein LOC240038 isoform 3

      Status: VALIDATED

      Source sequence(s)
      CT030661

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      22416246..22444640 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030249776.1 → XP_030105636.1  uncharacterized protein LOC240038 isoform X1

      UniProtKB/TrEMBL
      J3QM38
      Conserved Domains (3) summary
      COG5048
      Location:265 → 661
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:269 → 289
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:13 → 52
      KRAB; KRAB box

    2. XM_030249777.1 → XP_030105637.1  uncharacterized protein LOC240038 isoform X1

      UniProtKB/TrEMBL
      J3QM38
      Conserved Domains (3) summary
      COG5048
      Location:265 → 661
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:269 → 289
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:13 → 52
      KRAB; KRAB box
    Nucleotide Protein Strain
    Heading Accession and Version

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