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    Hat1 Histone acetyltransferase 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40716, updated on 9-Dec-2024

    Summary

    Official Symbol
    Hat1provided by FlyBase
    Official Full Name
    Histone acetyltransferase 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0037376
    Locus tag
    Dmel_CG2051
    See related
    AllianceGenome:FB:FBgn0037376
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG2051; Dmel\CG2051; dmHAG409; HAT1
    Summary
    Enables histone H4 acetyltransferase activity. Involved in CENP-A containing chromatin assembly. Predicted to be located in nucleus. Is expressed in dorsal epidermis primordium; embryonic dorsal epidermis; embryonic ventral epidermis; gut section; and ventral epidermis primordium. Orthologous to human HAT1 (histone acetyltransferase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Hat1 in Genome Data Viewer
    Location:
    83C4-83C4; 3-47.5 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (5787337..5789384, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (1613059..1615106, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Secretory 8 Neighboring gene uncharacterized protein Neighboring gene jagunal Neighboring gene katanin p60-like 1 Neighboring gene Regulatory particle non-ATPase 5 Neighboring gene Histone PARylation factor 1 Neighboring gene Proteasome assembly chaperone 1

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables histone H4 acetyltransferase activity  
    enables histone H4 acetyltransferase activity PubMed 
    enables histone acetyltransferase activity  
    enables histone binding  
    Component Evidence Code Pubs
    located_in nucleus  

    General protein information

    Preferred Names
    histone acetyltransferase 1
    Names
    CG2051-PA
    CG2051-PB
    Hat1-PA
    Hat1-PB
    NP_649587.1
    NP_731006.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      5787337..5789384 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_169106.2 → NP_731006.1  histone acetyltransferase 1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_731006.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0KIB3, Q4QQC4
      Related
      FBpp0078318
      Conserved Domains (2) summary
      pfam10394
      Location:10 → 173
      Hat1_N; Histone acetyl transferase HAT1 N-terminus
      pfam11221
      Location:368 → 403
      Med21; Subunit 21 of Mediator complex
    2. NM_141330.2 → NP_649587.1  histone acetyltransferase 1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649587.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0KIB3, Q4QQC4
      Related
      FBpp0078319
      Conserved Domains (2) summary
      pfam10394
      Location:10 → 173
      Hat1_N; Histone acetyl transferase HAT1 N-terminus
      pfam11221
      Location:368 → 403
      Med21; Subunit 21 of Mediator complex
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