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    CG5567 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39986, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG5567provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036760
    Locus tag
    Dmel_CG5567
    See related
    AllianceGenome:FB:FBgn0036760
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    24666141; Dmel\CG5567; Phos5567
    Summary
    Predicted to enable glycerol-3-phosphatase activity. Predicted to be involved in glycerol biosynthetic process. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Is expressed in several structures, including embryonic/larval midgut; embryonic/larval midgut primordium; and larval muscle cell. Orthologous to human PGP (phosphoglycolate phosphatase) and PDXP (pyridoxal phosphatase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG5567 in Genome Data Viewer
    Location:
    75A4-75A4; 3-45 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (17841540..17843544, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (17834640..17836644, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Glycine receptor Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45175 Neighboring gene Mediator complex subunit 19 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An insect farnesyl phosphatase homologous to the N-terminal domain of soluble epoxide hydrolase. Cao L, et al. Biochem Biophys Res Commun, 2009 Feb 27. PMID 19168029, Free PMC Article
    2. Flies without a spindle checkpoint. Buffin E, et al. Nat Cell Biol, 2007 May. PMID 17417628
    3. Harnessing the paradoxical phenotypes of APOE ɛ2 and APOE ɛ4 to identify genetic modifiers in Alzheimer's disease. Kim YW, et al. Alzheimers Dement, 2021 May. PMID 33576571, Free PMC Article
    4. The SIN3 deacetylase complex represses genes encoding mitochondrial proteins: implications for the regulation of energy metabolism. Pile LA, et al. J Biol Chem, 2003 Sep 26. PMID 12865422
    5. Functional requirements of protein kinases and phosphatases in the development of the Drosophila melanogaster wing. Ostalé CM, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599799, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables glycerol-3-phosphatase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in glycerol biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG5567-PA
    NP_649015.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      17841540..17843544 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140758.3 → NP_649015.2  uncharacterized protein Dmel_CG5567 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649015.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VVL5
      Related
      FBpp0074927
      Conserved Domains (3) summary
      TIGR01452
      Location:40 → 318
      PGP_euk; phosphoglycolate/pyridoxal phosphate phosphatase family
      pfam13242
      Location:235 → 318
      Hydrolase_like; HAD-hyrolase-like
      pfam13344
      Location:42 → 142
      Hydrolase_6; Haloacid dehalogenase-like hydrolase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T0U0 Q8T0U0
    Q9VVL5 Q9VVL5

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