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    CG3337 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42519, updated on 27-Dec-2024

    Summary

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    Official Symbol
    CG3337provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038871
    Locus tag
    Dmel_CG3337
    See related
    AllianceGenome:FB:FBgn0038871
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG3337; mat1
    Summary
    Predicted to enable protein-lysine N-methyltransferase activity. Predicted to be involved in regulation of mitochondrial ATP synthesis coupled proton transport. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Is expressed in adult head. Orthologous to several human genes including ATPSCKMT (ATP synthase c subunit lysine N-methyltransferase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3337 in Genome Data Viewer
    Location:
    93C7-93C7; 3-71 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (21220704..21223584, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (17048537..17049306, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene SET and MYND domain containing, class 5 Neighboring gene O-GlcNAcase Neighboring gene long non-coding RNA:CR44265 Neighboring gene Negative elongation factor A Neighboring gene ebony

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CDK7 regulates the mitochondrial localization of a tail-anchored proapoptotic protein, Hid. Morishita J, et al. Cell Rep, 2013 Dec 26. PMID 24360962, Free PMC Article
    2. Natural variation of ebony gene controlling thoracic pigmentation in Drosophila melanogaster. Takahashi A, et al. Genetics, 2007 Oct. PMID 17660557, Free PMC Article
    3. Automated identification of putative methyltransferases from genomic open reading frames. Katz JE, et al. Mol Cell Proteomics, 2003 Aug. PMID 12872006
    4. A gain-of-function screen identifying genes required for vein formation in the Drosophila melanogaster wing. Molnar C, et al. Genetics, 2006 Nov. PMID 16980395, Free PMC Article
    5. Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes. Hosono C, et al. Nat Cell Biol, 2015 Dec. PMID 26551273

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein-lysine N-methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein-lysine N-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-lysine N-methyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of mitochondrial ATP synthesis coupled proton transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3337-PA
    CG3337-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      21220704..21223584 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001316498.1 → NP_001303427.1  uncharacterized protein Dmel_CG3337, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VDC8
      Conserved Domains (1) summary
      pfam12847
      Location:78 → 167
      Methyltransf_18; Methyltransferase domain

    2. NM_142700.2 → NP_650957.1  uncharacterized protein Dmel_CG3337, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650957.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VDC8
      Related
      FBpp0083506
      Conserved Domains (1) summary
      pfam12847
      Location:78 → 167
      Methyltransf_18; Methyltransferase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VDC8 Q9VDC8

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