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    SmydA-9 SET and MYND domain containing, arthropod-specific, member 9 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31859, updated on 9-Dec-2024

    Summary

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    Official Symbol
    SmydA-9provided by FlyBase
    Official Full Name
    SET and MYND domain containing, arthropod-specific, member 9provided by FlyBase
    Primary source
    FLYBASE:FBgn0030102
    Locus tag
    Dmel_CG12119
    See related
    AllianceGenome:FB:FBgn0030102
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG12119; Dmel\CG12119; lincRNA.971
    Summary
    Predicted to enable histone deacetylase binding activity and protein-lysine N-methyltransferase activity. Predicted to be involved in negative regulation of gene expression. Located in cytoplasm and nucleus. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See SmydA-9 in Genome Data Viewer
    Location:
    8D1-8D1; 1-27 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (9206126..9210887, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (9100159..9104920, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene suppressor of rudimentary Neighboring gene Odorant-binding protein 8a Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phenotypic Plasticity through Transcriptional Regulation of the Evolutionary Hotspot Gene tan in Drosophila melanogaster. Gibert JM, et al. PLoS Genet, 2016 Aug. PMID 27508387, Free PMC Article
    2. Evolutionary History of the Smyd Gene Family in Metazoans: A Framework to Identify the Orthologs of Human Smyd Genes in Drosophila and Other Animal Species. Calpena E, et al. PLoS One, 2015. PMID 26230726, Free PMC Article
    3. A Drosophila Smyd4 homologue is a muscle-specific transcriptional modulator involved in development. Thompson EC, et al. PLoS One, 2008 Aug 20. PMID 18714374, Free PMC Article
    4. Transcriptome analysis of Drosophila melanogaster laboratory strains of different geographical origin after long-term laboratory maintenance. Zarubin M, et al. Ecol Evol, 2020 Jul. PMID 32760513, Free PMC Article
    5. Comparative genomic analysis of SET domain family reveals the origin, expansion, and putative function of the arthropod-specific SmydA genes as histone modifiers in insects. Jiang F, et al. Gigascience, 2017 Jun 1. PMID 28444351, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables histone deacetylase binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein-lysine N-methyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables protein-lysine N-methyltransferase activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of gene expression ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SET and MYND domain containing, arthropod-specific, member 9
    Names
    CG12119-PA
    CG12119-PB
    SmydA-9-PA
    SmydA-9-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      9206126..9210887 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298111.1 → NP_001285040.1  SET and MYND domain containing, arthropod-specific, member 9, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285040.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SYH2, Q9W373
      Conserved Domains (2) summary
      pfam00856
      Location:216 → 253
      SET; SET domain
      cl02566
      Location:25 → 66
      SET; SET domain

    2. NM_132311.3 → NP_572539.2  SET and MYND domain containing, arthropod-specific, member 9, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572539.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SYH2, Q9W373
      Related
      FBpp0071271
      Conserved Domains (2) summary
      pfam00856
      Location:216 → 253
      SET; SET domain
      cl02566
      Location:25 → 66
      SET; SET domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SYH2 Q8SYH2
    Q9W373 Q9W373

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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