Prosalpha4 Proteasome alpha4 subunit [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Prosalpha4provided by FlyBase
Official Full Name: Proteasome alpha4 subunitprovided by FlyBase
Primary source: FLYBASE:FBgn0004066
Locus tag: Dmel_CG3422
See related: AllianceGenome:FB:FBgn0004066
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: 28.1Pros; 3422; a4; alpha-4; Alpha-4; alpha4; alpha4_dm; CG3422; Dmel\CG3422; PROS-28.1; Pros-Dm28.1; PROS-Dm28.1; Pros28; pros28.1; Pros28.1; PROSA-28.1; PSA4_DROME
Summary: Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Part of proteasome core complex. Is expressed in several structures, including adult head; embryonic/larval midgut primordium; ganglia; germline cell; and imaginal disc. Orthologous to human PSMA7 (proteasome 20S subunit alpha 7) and PSMA8 (proteasome 20S subunit alpha 8). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (16276270..16277587)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (16170303..16171620)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
NOT enables peptidase activity	IKR Inferred from Key Residues more info

Process	Evidence Code	Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	IC Inferred by Curator more info	PubMed
involved_in ubiquitin-dependent protein catabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
part_of proteasome complex	IDA Inferred from Direct Assay more info	PubMed
part_of proteasome core complex	IDA Inferred from Direct Assay more info	PubMed
part_of proteasome core complex	IEA Inferred from Electronic Annotation more info
part_of proteasome core complex, alpha-subunit complex	IBA Inferred from Biological aspect of Ancestor more info
part_of proteasome core complex, alpha-subunit complex	IEA Inferred from Electronic Annotation more info
part_of proteasome core complex, alpha-subunit complex	ISS Inferred from Sequence or Structural Similarity more info

Names: 20s proteasome; CG3422-PA; Prosalpha4-PA; alpha-subunit of 20S proteasome; alpha4; proteasome 28kD subunit 1

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