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    C08B6.8 Exonuclease domain-containing protein;putative oligoribonuclease [ Caenorhabditis elegans ]

    Gene ID: 179411, updated on 27-Dec-2024

    Summary

    Official Symbol
    C08B6.8
    Official Full Name
    Exonuclease domain-containing protein;putative oligoribonuclease
    Primary source
    WormBase:WBGene00007429
    Locus tag
    CELE_C08B6.8
    See related
    AllianceGenome:WB:WBGene00007429
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable 3'-5'-RNA exonuclease activity and nucleic acid binding activity. Is expressed in several structures, including anal depressor muscle; egg-laying apparatus; excretory cell; intestine; and nervous system. Orthologous to human REXO2 (RNA exonuclease 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See C08B6.8 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    3
    Sequence:
    Chromosome: V; NC_003283.11 (10134643..10143014)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Proline-rich proteoglycan 2-like Neighboring gene SUMO-activating enzyme subunit aos-1 Neighboring gene WD repeat-containing protein 20 homolog;WD_REPEATS_REGION domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene pseudo Neighboring gene pseudo

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables 3'-5'-RNA exonuclease activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables exonuclease activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in nucleic acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Exonuclease domain-containing protein;putative oligoribonuclease
    NP_001256185.1
    • Confirmed by transcript evidence
    NP_001256186.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      10134643..10143014
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001269256.3NP_001256185.1  putative oligoribonuclease [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256185.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q17819
      Conserved Domains (1) summary
      cd06135
      Location:15185
      Orn; DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins
    2. NM_001269257.3NP_001256186.1  Exonuclease domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256186.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G3MU09
      Conserved Domains (1) summary
      cl10012
      Location:168
      DnaQ_like_exo; DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily