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    W02A11.1 tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A [ Caenorhabditis elegans ]

    Gene ID: 173142, updated on 9-Dec-2024

    Summary

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    Official Symbol
    W02A11.1
    Official Full Name
    tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A
    Primary source
    WormBase:WBGene00012192
    Locus tag
    CELE_W02A11.1
    See related
    AllianceGenome:WB:WBGene00012192
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable tRNA (adenine(58)-N1)-methyltransferase activity. Predicted to be involved in tRNA methylation. Predicted to be part of tRNA (m1A) methyltransferase complex. Predicted to be active in nucleus. Orthologous to human TRMT61A (tRNA methyltransferase 61A). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See W02A11.1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    6
    Sequence:
    Chromosome: I; NC_003279.8 (12730026..12732722, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene putative prefoldin subunit 3 Neighboring gene tRNA Neighboring gene Vacuolar protein-sorting-associated protein 25 Neighboring gene RING-type domain-containing protein Neighboring gene SUMO-activating enzyme subunit uba-2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA (adenine(58)-N1)-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in tRNA methylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in tRNA methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in tRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of tRNA (m1A) methyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of tRNA (m1A) methyltransferase complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A
    NP_001366896.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      12730026..12732722 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001381233.3 → NP_001366896.1  tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EGR8
      Conserved Domains (1) summary
      cl17173
      Location:67 → 306
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
    Nucleotide Protein
    Heading Accession and Version

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