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    Y48G1C.5 Tyrosine-protein phosphatase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 171595, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y48G1C.5
    Official Full Name
    Tyrosine-protein phosphatase domain-containing protein
    Primary source
    WormBase:WBGene00021678
    Locus tag
    CELE_Y48G1C.5
    See related
    AllianceGenome:WB:WBGene00021678
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in protein dephosphorylation. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y48G1C.5 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    12
    Sequence:
    Chromosome: I; NC_003279.8 (55293..64066, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Anaphase-promoting complex subunit 10 Neighboring gene CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Neighboring gene Serine-threonine/tyrosine-protein kinase catalytic domain-containing protein;Tyrosine-protein kinase csk-1 Neighboring gene Myotubularin phosphatase domain-containing protein Neighboring gene HTH CENPB-type domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Tyrosine-protein phosphatase domain-containing protein
    NP_490668.4
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      55293..64066 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058267.6 → NP_490668.4  Tyrosine-protein phosphatase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_490668.4

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9BL78
      Conserved Domains (2) summary
      pfam02206
      Location:47 → 111
      WSN; Domain of unknown function
      cl21483
      Location:940 → 1085
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    Nucleotide Protein
    Heading Accession and Version

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