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    flp-17 FMRF-Like Peptide [ Caenorhabditis elegans ]

    Gene ID: 178498, updated on 9-Dec-2024

    Summary

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    Official Symbol
    flp-17
    Official Full Name
    FMRF-Like Peptide
    Primary source
    WormBase:WBGene00001460
    Locus tag
    CELE_C52D10.11
    See related
    AllianceGenome:WB:WBGene00001460
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in negative regulation of egg-laying behavior. Located in neuron projection and neuronal cell body. Is expressed in nerve ring and neurons. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See flp-17 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    3
    Sequence:
    Chromosome: IV; NC_003282.8 (17190204..17191891, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene DUF4140 domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterizing a standardized BioPart for BAG-specific expression in C. elegans. Qian X, et al. MicroPubl Biol, 2024. PMID 38545436, Free PMC Article
    2. A chemoreceptor that detects molecular carbon dioxide. Smith ES, et al. J Biol Chem, 2013 Dec 27. PMID 24240097, Free PMC Article
    3. Oxygen-sensing neurons reciprocally regulate peripheral lipid metabolism via neuropeptide signaling in Caenorhabditis elegans. Hussey R, et al. PLoS Genet, 2018 Mar. PMID 29579048, Free PMC Article
    4. Axial patterning of C. elegans male sensilla identities by selector genes. Lints R, et al. Dev Biol, 2004 May 1. PMID 15081363
    5. FMRFamide neuropeptides and acetylcholine synergistically inhibit egg-laying by C. elegans. Ringstad N, et al. Nat Neurosci, 2008 Oct. PMID 18806786, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in negative regulation of egg-laying behavior IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in neuropeptide signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in neuron projection IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in neuronal cell body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    FMRF-Like Peptide
    NP_503051.1
    • Product from WormBase gene class flp;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      17190204..17191891 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_070650.5 → NP_503051.1  FMRF-Like Peptide [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_503051.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A3QM96
    Nucleotide Protein
    Heading Accession and Version

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