eif-1.A Eukaryotic translation initiation factor 4C [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: eif-1.A
Official Full Name: Eukaryotic translation initiation factor 4C
Primary source: WormBase:WBGene00019162
Locus tag: CELE_H06H21.3
See related: AllianceGenome:WB:WBGene00019162
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be active in cytoplasm. Is expressed in several structures, including anal depressor muscle; head; rectal gland cell; reproductive system; and tail. Orthologous to human EIF1AX (eukaryotic translation initiation factor 1A X-linked) and EIF1AY (eukaryotic translation initiation factor 1A Y-linked). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See eif-1.A in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 3

Sequence:: Chromosome: IV; NC_003282.8 (4810934..4811983)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

H06H21.3 (e-PCR)
- UniSTS:316883

H06H21.7 (e-PCR)
- UniSTS:316885

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables translation initiation factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables translation initiation factor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in translation	IEA Inferred from Electronic Annotation more info
involved_in translational initiation	IBA Inferred from Biological aspect of Ancestor more info
involved_in translational initiation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Eukaryotic translation initiation factor 4C

NP_500650.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

4810934..4811983

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_068249.7 → NP_500650.1 Eukaryotic translation initiation factor 4C [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_500650.1

Status: REVIEWED

UniProtKB/TrEMBL

Q9TXU7

Conserved Domains (1) summary

cl09927
Location:1 → 140

S1_like; Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain. Both domains ...