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    Y47D9A.1 Nucleotidyl transferase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172033, updated on 9-Dec-2024

    Summary

    Official Symbol
    Y47D9A.1
    Official Full Name
    Nucleotidyl transferase domain-containing protein
    Primary source
    WormBase:WBGene00021628
    Locus tag
    CELE_Y47D9A.1
    See related
    AllianceGenome:WB:WBGene00021628
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable transferase activity. Predicted to be involved in biosynthetic process. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in alacrima, achalasia, and impaired intellectual development syndrome. Orthologous to human GMPPA (GDP-mannose pyrophosphorylase A). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See Y47D9A.1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    8
    Sequence:
    Chromosome: I; NC_003279.8 (4303930..4308244)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene CTD small phosphatase-like protein 3;FCP1 homology domain-containing protein Neighboring gene ABC transporter permease Neighboring gene ncRNA Neighboring gene Calponin-homology (CH) domain-containing protein;KASH domain-containing protein;Nuclear anchorage protein 1 Neighboring gene ncRNA

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Nucleotidyl transferase domain-containing protein
    NP_491349.1
    • Confirmed by transcript evidence
    NP_491350.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      4303930..4308244
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058948.5NP_491349.1  Nucleotidyl transferase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491349.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N4V3
      Conserved Domains (2) summary
      cd06428
      Location:5244
      M1P_guanylylT_A_like_N; N-terminal domain of M1P_guanylyl_A_ like proteins are likely to be a isoform of GDP-mannose pyrophosphorylase
      cl00160
      Location:269336
      LbetaH; Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes ...
    2. NM_058949.5NP_491350.1  Nucleotidyl transferase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491350.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N4V2
      Conserved Domains (2) summary
      cd06428
      Location:5237
      M1P_guanylylT_A_like_N; N-terminal domain of M1P_guanylyl_A_ like proteins are likely to be a isoform of GDP-mannose pyrophosphorylase
      cl00160
      Location:262329
      LbetaH; Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes ...