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    cri-3 Conserved regulator of innate immunity protein 3 [ Caenorhabditis elegans ]

    Gene ID: 175441, updated on 9-Dec-2024

    Summary

    Official Symbol
    cri-3
    Official Full Name
    Conserved regulator of innate immunity protein 3
    Primary source
    WormBase:WBGene00010303
    Locus tag
    CELE_F59A2.3
    See related
    AllianceGenome:WB:WBGene00010303
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in cytosolic ribosome assembly. Predicted to be located in mitochondrial matrix. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 33. Orthologous to human C1QBP (complement C1q binding protein). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See cri-3 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    4
    Sequence:
    Chromosome: III; NC_003281.10 (3396585..3397627)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene E3 ubiquitin-protein ligase hecw-1 Neighboring gene tRNA-Lys Neighboring gene ncRNA Neighboring gene ELMO domain-containing protein;ELMO domain-containing protein C56G7.3 Neighboring gene Myosin regulatory light chain Neighboring gene Pre-mRNA cleavage complex subunit Clp1 C-terminal domain-containing protein;Protein clpf-1 Neighboring gene Nuclear Pore complex Protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cytosolic ribosome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in negative regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrial matrix IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Conserved regulator of innate immunity protein 3
    NP_001379055.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      3396585..3397627
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001393306.1NP_001379055.1  Conserved regulator of innate immunity protein 3 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q21018
      Conserved Domains (1) summary
      pfam02330
      Location:46228
      MAM33; Mitochondrial glycoprotein