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    F53E4.1 Kelch domain-containing protein 10;Kelch domain-containing protein 3 [ Caenorhabditis elegans ]

    Gene ID: 180050, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F53E4.1
    Official Full Name
    Kelch domain-containing protein 10;Kelch domain-containing protein 3
    Primary source
    WormBase:WBGene00009978
    Locus tag
    CELE_F53E4.1
    See related
    AllianceGenome:WB:WBGene00009978
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable chromatin binding activity. Predicted to be active in cytoplasm. Is expressed in several structures, including arcade cell; hypodermis; intestine; nervous system; and reproductive system. Orthologous to human KLHDC3 (kelch domain containing 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F53E4.1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    9
    Sequence:
    Chromosome: V; NC_003283.11 (15652430..15668300, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene DUF148 domain-containing protein Neighboring gene Serpentine receptor class gamma Neighboring gene Ovule protein Neighboring gene Conserved plasma membrane protein Neighboring gene DUF1084 domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Kelch domain-containing protein 10;Kelch domain-containing protein 3
    NP_001122948.1
    • Confirmed by transcript evidence
    NP_001256679.1
    • Confirmed by transcript evidence
    NP_001368706.1
    • Partially confirmed by transcript evidence
    NP_001379191.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      15652430..15668300 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001129476.5 → NP_001122948.1  Kelch domain-containing protein 3 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122948.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EBG8
      Conserved Domains (3) summary
      sd00038
      Location:144 → 186
      Kelch; KELCH repeat [structural motif]
      pfam07646
      Location:93 → 134
      Kelch_2; Kelch motif
      pfam13415
      Location:153 → 204
      Kelch_3; Galactose oxidase, central domain

    2. NM_001392674.1 → NP_001379191.1  Kelch domain-containing protein 3 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EEG5
      Conserved Domains (3) summary
      PLN02153
      Location:73 → 332
      PLN02153; epithiospecifier protein
      sd00038
      Location:144 → 186
      Kelch; KELCH repeat [structural motif]
      pfam07646
      Location:13 → 61
      Kelch_2; Kelch motif

    3. NM_001380833.1 → NP_001368706.1  Kelch domain-containing protein 3 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A3B1E9Z3
      Conserved Domains (3) summary
      PLN02153
      Location:79 → 338
      PLN02153; epithiospecifier protein
      sd00038
      Location:150 → 192
      Kelch; KELCH repeat [structural motif]
      pfam07646
      Location:19 → 67
      Kelch_2; Kelch motif

    4. NM_001269750.3 → NP_001256679.1  Kelch domain-containing protein 10 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256679.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H9G305
      Conserved Domains (2) summary
      sd00038
      Location:25 → 74
      Kelch; KELCH repeat [structural motif]
      pfam13415
      Location:34 → 84
      Kelch_3; Galactose oxidase, central domain
    Nucleotide Protein
    Heading Accession and Version

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