C01G10.9 Methylthioribose-1-phosphate isomerase [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: C01G10.9
Official Full Name: Methylthioribose-1-phosphate isomerase
Primary source: WormBase:WBGene00007236
Locus tag: CELE_C01G10.9
See related: AllianceGenome:WB:WBGene00007236
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable S-methyl-5-thioribose-1-phosphate isomerase activity. Predicted to be involved in L-methionine salvage from methylthioadenosine. Predicted to be located in cytoplasm and nucleus. Orthologous to human MRI1 (methylthioribose-1-phosphate isomerase 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See C01G10.9 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 4

Sequence:: Chromosome: V; NC_003283.11 (15082530..15084147)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C01G10.9 (e-PCR)
- UniSTS:321175

C01G10.10 (e-PCR)
- UniSTS:321176

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables S-methyl-5-thioribose-1-phosphate isomerase activity	IBA Inferred from Biological aspect of Ancestor more info
enables S-methyl-5-thioribose-1-phosphate isomerase activity	IEA Inferred from Electronic Annotation more info
enables isomerase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in L-methionine salvage from S-adenosylmethionine	IEA Inferred from Electronic Annotation more info
involved_in L-methionine salvage from methylthioadenosine	IBA Inferred from Biological aspect of Ancestor more info
involved_in L-methionine salvage from methylthioadenosine	IEA Inferred from Electronic Annotation more info
involved_in biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in metabolic process	IEA Inferred from Electronic Annotation more info
involved_in methionine biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Methylthioribose-1-phosphate isomerase

NP_506714.1

Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

15082530..15084147

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_074313.8 → NP_506714.1 Methylthioribose-1-phosphate isomerase [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_506714.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q93169

Conserved Domains (2) summary

cl00348
Location:27 → 353

GCD2; Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family [Translation, ribosomal structure and biogenesis]

pfam01008
Location:66 → 357

IF-2B; Initiation factor 2 subunit family