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    lin-38 C2H2-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 190028, updated on 9-Dec-2024

    Summary

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    Official Symbol
    lin-38
    Official Full Name
    C2H2-type domain-containing protein
    Primary source
    WormBase:WBGene00013006
    Locus tag
    CELE_Y48E1B.7
    See related
    AllianceGenome:WB:WBGene00013006
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in negative regulation of vulval development. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See lin-38 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    9
    Sequence:
    Chromosome: II; NC_003280.10 (13575925..13585523)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Geranylgeranyl transferase type I subunit beta;Geranylgeranyl transferase type-1 subunit beta Neighboring gene Large ribosomal subunit protein mL37 Neighboring gene Nucleotide-diphospho-sugar transferase domain-containing protein Neighboring gene C-type lectin domain-containing protein Neighboring gene C-type lectin domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. dpl-1 DP and efl-1 E2F act with lin-35 Rb to antagonize Ras signaling in C. elegans vulval development. Ceol CJ, et al. Mol Cell, 2001 Mar. PMID 11463372
    2. The multivulva phenotype of certain Caenorhabditis elegans mutants results from defects in two functionally redundant pathways. Ferguson EL, et al. Genetics, 1989 Sep. PMID 2806880, Free PMC Article
    3. The LIN-15A and LIN-56 transcriptional regulators interact to negatively regulate EGF/Ras signaling in Caenorhabditis elegans vulval cell-fate determination. Davison EM, et al. Genetics, 2011 Mar. PMID 21196525, Free PMC Article
    4. The histone demethylase UTX enables RB-dependent cell fate control. Wang JK, et al. Genes Dev, 2010 Feb 15. PMID 20123895, Free PMC Article
    5. Caenorhabditis elegans lin-13, a member of the LIN-35 Rb class of genes involved in vulval development, encodes a protein with zinc fingers and an LXCXE motif. Meléndez A, et al. Genetics, 2000 Jul. PMID 10880475, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in negative regulation of vulval development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    C2H2-type domain-containing protein
    NP_496852.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      13575925..13585523
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064451.5 → NP_496852.3  C2H2-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496852.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      O45950
    Nucleotide Protein
    Heading Accession and Version

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