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    mbf-1 HTH cro/C1-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 178071, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mbf-1
    Official Full Name
    HTH cro/C1-type domain-containing protein
    Primary source
    WormBase:WBGene00003148
    Locus tag
    CELE_H21P03.1
    See related
    AllianceGenome:WB:WBGene00003148
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA binding activity. Predicted to be active in nucleus. Is expressed in several structures, including enteric muscle; hermaphrodite gonad; hypodermis; intestine; and nervous system. Orthologous to human EDF1 (endothelial differentiation related factor 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See mbf-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    2
    Sequence:
    Chromosome: IV; NC_003282.8 (11479354..11480369, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ABC transporter domain-containing protein Neighboring gene ncRNA Neighboring gene putative manganese-transporting ATPase catp-8 Neighboring gene ncRNA Neighboring gene Non-structural maintenance of chromosomes element 4 Neighboring gene ncRNA Neighboring gene Phosphatidylcholine:ceramide cholinephosphotransferase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of proteins and miRNAs that specifically bind an mRNA in vivo. Theil K, et al. Nat Commun, 2019 Sep 16. PMID 31527589, Free PMC Article
    2. A 4D single-cell protein atlas of transcription factors delineates spatiotemporal patterning during embryogenesis. Ma X, et al. Nat Methods, 2021 Aug. PMID 34312566
    3. CCAR-1 works together with the U2AF large subunit UAF-1 to regulate alternative splicing. Lugano DI, et al. RNA Biol, 2024 Jan. PMID 38126797, Free PMC Article
    4. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
    5. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    HTH cro/C1-type domain-containing protein
    NP_502166.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      11479354..11480369 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069765.8 → NP_502166.1  HTH cro/C1-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502166.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XTV4
      Conserved Domains (2) summary
      cl26727
      Location:19 → 145
      aMBF1; Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and HTH domains [Translation, ribosomal structure and biogenesis]
      pfam08523
      Location:12 → 79
      MBF1; Multiprotein bridging factor 1
    Nucleotide Protein
    Heading Accession and Version

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