adk-1 Adenosine kinase [Caenorhabditis elegans] - Gene

Summary

Official Symbol: adk-1
Official Full Name: Adenosine kinase
Primary source: WormBase:WBGene00011128
Locus tag: CELE_R07H5.8
See related: AllianceGenome:WB:WBGene00011128
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable adenosine kinase activity. Predicted to be involved in purine nucleobase metabolic process. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including excretory cell; hypodermis; intestine; pharynx; and reproductive system. Human ortholog(s) of this gene implicated in hypermethioninemia due to adenosine kinase deficiency. Orthologous to human ADK (adenosine kinase). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables adenosine kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables adenosine kinase activity	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in AMP salvage	IEA Inferred from Electronic Annotation more info
involved_in nucleobase-containing compound biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in nucleobase-containing small molecule metabolic process	IEA Inferred from Electronic Annotation more info
involved_in phosphate-containing compound metabolic process	IEA Inferred from Electronic Annotation more info
involved_in purine nucleobase metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in purine ribonucleoside salvage	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

NP_502104.1

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The following sections contain reference sequences that belong to a specific genome build. Explain