vha-10 putative V-type proton ATPase subunit G [Caenorhabditis elegans] - Gene

Summary

Official Symbol: vha-10
Official Full Name: putative V-type proton ATPase subunit G
Primary source: WormBase:WBGene00006919
Locus tag: CELE_F46F11.5
See related: AllianceGenome:WB:WBGene00006919
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable ATP hydrolysis activity and proton-transporting ATPase activity, rotational mechanism. Involved in positive regulation of programmed cell death and programmed cell death. Predicted to be located in presynapse. Predicted to be part of vacuolar proton-transporting V-type ATPase, V1 domain. Orthologous to several human genes including ATP6V1G2 (ATPase H+ transporting V1 subunit G2). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables ATP hydrolysis activity	IBA Inferred from Biological aspect of Ancestor more info
enables proton transmembrane transporter activity	NAS Non-traceable Author Statement more info	PubMed
enables proton-transporting ATPase activity, rotational mechanism	IBA Inferred from Biological aspect of Ancestor more info
enables proton-transporting ATPase activity, rotational mechanism	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in ATP biosynthetic process	NAS Non-traceable Author Statement more info	PubMed
involved_in positive regulation of programmed cell death	IGI Inferred from Genetic Interaction more info	PubMed
involved_in programmed cell death	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in proton transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in proton transmembrane transport	NAS Non-traceable Author Statement more info	PubMed
involved_in synaptic vesicle lumen acidification	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in presynapse	IEA Inferred from Electronic Annotation more info
part_of vacuolar proton-transporting V-type ATPase complex	IEA Inferred from Electronic Annotation more info
part_of vacuolar proton-transporting V-type ATPase complex	NAS Non-traceable Author Statement more info	PubMed
part_of vacuolar proton-transporting V-type ATPase, V1 domain	IBA Inferred from Biological aspect of Ancestor more info

NP_491641.1

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