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    trx-5 Thioredoxin domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 186914, updated on 9-Dec-2024

    Summary

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    Official Symbol
    trx-5
    Official Full Name
    Thioredoxin domain-containing protein
    Primary source
    WormBase:WBGene00019349
    Locus tag
    CELE_K02H11.6
    See related
    AllianceGenome:WB:WBGene00019349
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in photoreceptor cell maintenance and sensory perception. Orthologous to human NXNL2 (nucleoredoxin like 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See trx-5 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    3
    Sequence:
    Chromosome: V; NC_003283.11 (1533892..1534415, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Glycosyltransferase family 92 protein Neighboring gene pseudo Neighboring gene FRIGIDA-like protein Neighboring gene Nose resistant-to-fluoxetine protein N-terminal domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The cytoplasmic thioredoxin system in Caenorhabditis elegans affords protection from methylmercury in an age-specific manner. Ruszkiewicz JA, et al. Neurotoxicology, 2018 Sep. PMID 30138651
    2. The Redox System in C. elegans, a Phylogenetic Approach. Johnston AD, et al. J Toxicol, 2012. PMID 22899914, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in photoreceptor cell maintenance IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sensory perception IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Thioredoxin domain-containing protein
    NP_503440.2
    • Predicted

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      1533892..1534415 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_071039.2 → NP_503440.2  Thioredoxin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_503440.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O61985
      Conserved Domains (1) summary
      cd02964
      Location:9 → 127
      TryX_like_family; Tryparedoxin (TryX)-like family; composed of TryX and related proteins including nucleoredoxin (NRX), rod-derived cone viability factor (RdCVF) and the nematode homolog described as a 16-kD class of TRX. Most members of this family, except RdCVF, are ...
    Nucleotide Protein
    Heading Accession and Version

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