taf-6.1 TAF (TBP-associated transcription factor) family;TAF6 C-terminal HEAT repeat domain-containing protein;Transcription initiation factor TFIID subunit 6 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: taf-6.1
Official Full Name: TAF (TBP-associated transcription factor) family;TAF6 C-terminal HEAT repeat domain-containing protein;Transcription initiation factor TFIID subunit 6
Primary source: WormBase:WBGene00006387
Locus tag: CELE_W09B6.2
See related: AllianceGenome:WB:WBGene00006387
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable transcription coactivator activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex. Orthologous to human TAF6 (TATA-box binding protein associated factor 6). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See taf-6.1 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 8

Sequence:: Chromosome: II; NC_003280.10 (1127976..1132352)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

W09B6.2 (e-PCR)
- UniSTS:319721

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
contributes_to RNA polymerase II general transcription initiation factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II general transcription initiation factor activity	IEA Inferred from Electronic Annotation more info
enables protein heterodimerization activity	IEA Inferred from Electronic Annotation more info
enables transcription coactivator activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in RNA polymerase II preinitiation complex assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in transcription initiation at RNA polymerase II promoter	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of SAGA complex	IEA Inferred from Electronic Annotation more info
part_of SLIK (SAGA-like) complex	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of transcription factor TFIID complex	IBA Inferred from Biological aspect of Ancestor more info
part_of transcription factor TFIID complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: TAF (TBP-associated transcription factor) family;TAF6 C-terminal HEAT repeat domain-containing protein;Transcription initiation factor TFIID subunit 6

NP_001305234.1

Confirmed by transcript evidence

NP_001305235.1

Confirmed by transcript evidence

NP_001305236.1

Confirmed by transcript evidence

NP_001305237.1

Product from WormBase gene class taf;
Confirmed by transcript evidence

NP_493919.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

1127976..1132352

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_061518.9 → NP_493919.1 Transcription initiation factor TFIID subunit 6 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_493919.1

Status: REVIEWED

UniProtKB/TrEMBL

Q9GZI6

Conserved Domains (2) summary

COG5095
Location:32 → 404

TAF6; Transcription initiation factor TFIID, subunit TAF6 (also component of histone acetyltransferase SAGA) [Transcription]

cd08050
Location:225 → 446

TAF6C; C-terminal domain of TATA Binding Protein (TBP) Associated Factor 6 (TAF6)
NM_001318305.3 → NP_001305234.1 TAF6 C-terminal HEAT repeat domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A0S4XRY0

Conserved Domains (1) summary

cd08050
Location:151 → 372

TAF6C; C-terminal domain of TATA Binding Protein (TBP) Associated Factor 6 (TAF6)
NM_001318306.3 → NP_001305235.1 TAF6 C-terminal HEAT repeat domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A0S4XR63

Conserved Domains (1) summary

cd08050
Location:24 → 245

TAF6C; C-terminal domain of TATA Binding Protein (TBP) Associated Factor 6 (TAF6)
NM_001318307.3 → NP_001305236.1 TAF6 C-terminal HEAT repeat domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A0S4XRA5

Conserved Domains (1) summary

cd08050
Location:5 → 140

TAF6C; C-terminal domain of TATA Binding Protein (TBP) Associated Factor 6 (TAF6)
NM_001318308.3 → NP_001305237.1 TAF (TBP-associated transcription factor) family [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A0S4XR87