ubxn-6 UBX domain-containing protein 6 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: ubxn-6
Official Full Name: UBX domain-containing protein 6
Primary source: WormBase:WBGene00019163
Locus tag: CELE_H06H21.6
See related: AllianceGenome:WB:WBGene00019163
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to be active in cytoplasm. Is expressed in nervous system and pharynx. Orthologous to human UBXN6 (UBX domain protein 6). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See ubxn-6 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 4

Sequence:: Chromosome: IV; NC_003282.8 (4807426..4809497, complement)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The amount of UBXN-6 was markedly increased upon starvation, but not with the treatment of tunicamycin and rapamycin. The induction upon starvation is a unique characteristic for UBXN-6 among C-terminal cofactors of CDC-48.
Title: Functional characterization of UBXN-6, a C-terminal cofactor of CDC-48, in C. elegans.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

H06H21.3 (e-PCR)
- UniSTS:316883

H06H21.6 (e-PCR)
- UniSTS:316884

H06H21.7 (e-PCR)
- UniSTS:316885

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: UBX domain-containing protein 6

NP_500648.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

4807426..4809497 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_068247.8 → NP_500648.2 UBX domain-containing protein 6 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_500648.2

Status: REVIEWED

UniProtKB/Swiss-Prot

Q8WTJ4

Conserved Domains (2) summary

cd10460
Location:166 → 262

PUB_UBXD1; PNGase/UBA or UBX (PUB) domain of UBXD1

cl00155
Location:334 → 410

UBQ; Ubiquitin-like proteins