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    gei-4 BZIP domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 175195, updated on 9-Dec-2024

    Summary

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    Official Symbol
    gei-4
    Official Full Name
    BZIP domain-containing protein
    Primary source
    WormBase:WBGene00001561
    Locus tag
    CELE_W07B3.2
    See related
    AllianceGenome:WB:WBGene00001561
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in negative regulation of Ras protein signal transduction and negative regulation of vulval development. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See gei-4 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    10
    Sequence:
    Chromosome: III; NC_003281.10 (344306..354694, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ADF-H domain-containing protein Neighboring gene PDZ domain-containing protein Neighboring gene ncRNA Neighboring gene Phosphoinositide phospholipase C Neighboring gene GST N-terminal domain-containing protein;Glutathione-dependent dehydroascorbate reductase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Predicting aging/longevity-related genes in the nematode Caenorhabditis elegans. Witten TM, et al. Chem Biodivers, 2007 Nov. PMID 18027377
    2. Function, dynamics and evolution of network motif modules in integrated gene regulatory networks of worm and plant. Defoort J, et al. Nucleic Acids Res, 2018 Jul 27. PMID 29873777, Free PMC Article
    3. High qualitative and quantitative conservation of alternative splicing in Caenorhabditis elegans and Caenorhabditis briggsae. Rukov JL, et al. Mol Biol Evol, 2007 Apr. PMID 17272679
    4. Isolation of the interacting molecules with GEX-3 by a novel functional screening. Tsuboi D, et al. Biochem Biophys Res Commun, 2002 Apr 5. PMID 11922622
    5. Genome-wide RNAi screen and in vivo protein aggregation reporters identify degradation of damaged proteins as an essential hypertonic stress response. Choe KP, et al. Am J Physiol Cell Physiol, 2008 Dec. PMID 18829898, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of Ras protein signal transduction IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    involved_in negative regulation of vulval development IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    BZIP domain-containing protein
    NP_001022811.1
    • Partially confirmed by transcript evidence
    NP_001367960.1
    • Confirmed by transcript evidence
    NP_001370795.1
    • Confirmed by transcript evidence
    NP_001380017.1
    • Partially confirmed by transcript evidence
    NP_001380018.1
    • Partially confirmed by transcript evidence
    NP_497190.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      344306..354694 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001381690.2 → NP_001367960.1  BZIP domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L0F5
      Conserved Domains (1) summary
      PTZ00121
      Location:110 → 387
      PTZ00121; MAEBL; Provisional

    2. NM_064789.6 → NP_497190.1  BZIP domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497190.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L0F6
      Conserved Domains (1) summary
      PTZ00121
      Location:133 → 410
      PTZ00121; MAEBL; Provisional

    3. NM_001393253.1 → NP_001380018.1  BZIP domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8ITW3
      Conserved Domains (1) summary
      PTZ00121
      Location:133 → 395
      PTZ00121; MAEBL; Provisional

    4. NM_001384004.2 → NP_001370795.1  BZIP domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L0F7
      Conserved Domains (1) summary
      PTZ00121
      Location:133 → 390
      PTZ00121; MAEBL; Provisional

    5. NM_001027640.5 → NP_001022811.1  BZIP domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022811.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q65CL5
      Conserved Domains (1) summary
      PTZ00121
      Location:109 → 368
      PTZ00121; MAEBL; Provisional

    6. NM_001393254.1 → NP_001380017.1  BZIP domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L0F8
    Nucleotide Protein
    Heading Accession and Version

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