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    tag-244 CUB_2 domain-containing protein;IgGFc_binding domain-containing protein;Secreted protein [ Caenorhabditis elegans ]

    Gene ID: 176962, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tag-244
    Official Full Name
    CUB_2 domain-containing protein;IgGFc_binding domain-containing protein;Secreted protein
    Primary source
    WormBase:WBGene00044073
    Locus tag
    CELE_C34H4.3
    See related
    AllianceGenome:WB:WBGene00044073
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in innate immune response. Is expressed in intestine. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See tag-244 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    8
    Sequence:
    Chromosome: IV; NC_003282.8 (1550878..1553119)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene C2H2-type domain-containing protein Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein Neighboring gene CUB_2 domain-containing protein Neighboring gene Amine oxidase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A conserved role for a GATA transcription factor in regulating epithelial innate immune responses. Shapira M, et al. Proc Natl Acad Sci U S A, 2006 Sep 19. PMID 16968778, Free PMC Article
    2. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Okahata M, et al. Sci Rep, 2024 Mar 5. PMID 38443452, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in innate immune response HEP PubMed 

    General protein information

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    Preferred Names
    CUB_2 domain-containing protein;IgGFc_binding domain-containing protein;Secreted protein
    NP_001294313.1
    • Confirmed by transcript evidence
    NP_001294314.1
    • Confirmed by transcript evidence
    NP_500095.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      1550878..1553119
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067694.4 → NP_500095.1  CUB_2 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500095.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O45142
      Conserved Domains (1) summary
      pfam03409
      Location:41 → 379
      Glycoprotein; Transmembrane glycoprotein

    2. NM_001307384.1 → NP_001294313.1  Secreted protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294313.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PE42
      Conserved Domains (1) summary
      pfam03409
      Location:41 → 168
      Glycoprotein; Transmembrane glycoprotein

    3. NM_001307385.3 → NP_001294314.1  IgGFc_binding domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294314.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PAV5
      Conserved Domains (1) summary
      pfam03409
      Location:41 → 246
      Glycoprotein; Transmembrane glycoprotein
    Nucleotide Protein
    Heading Accession and Version

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