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    lelo-1 GSKIP domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 174032, updated on 9-Dec-2024

    Summary

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    Official Symbol
    lelo-1
    Official Full Name
    GSKIP domain-containing protein
    Primary source
    WormBase:WBGene00020782
    Locus tag
    CELE_T24H7.3
    See related
    AllianceGenome:WB:WBGene00020782
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable kinase regulator activity and protein kinase A binding activity. Predicted to be involved in regulation of canonical Wnt signaling pathway. Predicted to be active in cytoplasm. Orthologous to human GSKIP (GSK3B interacting protein). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See lelo-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003280.10 (6246357..6247219)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Phospholipid-transporting ATPase Neighboring gene Small vasohibin-binding protein Neighboring gene Biogenesis of lysosome-related organelles complex 1 subunit 4 Neighboring gene Hypoxia up-regulated protein 1 Neighboring gene ncRNA Neighboring gene Mitochondrial prohibitin complex protein 2 Neighboring gene protein of unknown function DB domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables kinase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase A binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    GSKIP domain-containing protein
    NP_495248.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      6246357..6247219
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_062847.10 → NP_495248.1  GSKIP domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495248.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22757
    Nucleotide Protein
    Heading Accession and Version

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