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    slfl-3 Schlafen-like protein 3 [ Caenorhabditis elegans ]

    Gene ID: 183245, updated on 9-Dec-2024

    Summary

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    Official Symbol
    slfl-3
    Official Full Name
    Schlafen-like protein 3
    Primary source
    WormBase:WBGene00016460
    Locus tag
    CELE_C35E7.8
    See related
    AllianceGenome:WB:WBGene00016460
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in primary piRNA processing. Located in mitochondrion. Part of endoribonuclease complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See slfl-3 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    6
    Sequence:
    Chromosome: I; NC_003279.8 (10808590..10810489)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene RING-type E3 ubiquitin transferase Neighboring gene Major sperm protein Neighboring gene tRNA-Asp Neighboring gene Tyrosine-protein kinase Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. piRNA processing by a trimeric Schlafen-domain nuclease. Podvalnaya N, et al. Nature, 2023 Oct. PMID 37758951, Free PMC Article
    2. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
    3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in primary piRNA processing IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum HDA PubMed 
    part_of endoribonuclease complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Schlafen-like protein 3
    NP_492825.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      10808590..10810489
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060424.7 → NP_492825.3  Schlafen-like protein 3 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492825.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O61766
    Nucleotide Protein
    Heading Accession and Version

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