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    pqn-74 Chitin-binding type-2 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 178294, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pqn-74
    Official Full Name
    Chitin-binding type-2 domain-containing protein
    Primary source
    WormBase:WBGene00004156
    Locus tag
    CELE_W02A2.3
    See related
    AllianceGenome:WB:WBGene00004156
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable chitin binding activity. Involved in endoplasmic reticulum unfolded protein response. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See pqn-74 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    6
    Sequence:
    Chromosome: IV; NC_003282.8 (13329507..13331406, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Delta(12) fatty acid desaturase fat-2;Fatty acid desaturase Neighboring gene Fatty-acid and retinol-binding protein 1 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span. Viswanathan M, et al. Dev Cell, 2005 Nov. PMID 16256736
    2. A novel biochemical method to identify target genes of individual microRNAs: identification of a new Caenorhabditis elegans let-7 target. Andachi Y. RNA, 2008 Nov. PMID 18824511, Free PMC Article
    3. A survival pathway for Caenorhabditis elegans with a blocked unfolded protein response. Urano F, et al. J Cell Biol, 2002 Aug 19. PMID 12186849, Free PMC Article
    4. Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network. Tewari M, et al. Mol Cell, 2004 Feb 27. PMID 14992718
    5. A spatiotemporal reconstruction of the C. elegans pharyngeal cuticle reveals a structure rich in phase-separating proteins. Kamal M, et al. Elife, 2022 Oct 19. PMID 36259463, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables chitin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum unfolded protein response HEP PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Chitin-binding type-2 domain-containing protein
    NP_001380173.1
    • Confirmed by transcript evidence
    NP_502562.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      13329507..13331406 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_070161.5 → NP_502562.1  Chitin-binding type-2 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502562.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XUB6
      Conserved Domains (1) summary
      smart00494
      Location:271 → 325
      ChtBD2; Chitin-binding domain type 2

    2. NM_001392428.1 → NP_001380173.1  Chitin-binding type-2 domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A061AKS9
      Conserved Domains (1) summary
      smart00494
      Location:151 → 205
      ChtBD2; Chitin-binding domain type 2
    Nucleotide Protein
    Heading Accession and Version

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