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    shc-2 SH2 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 173860, updated on 9-Dec-2024

    Summary

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    Official Symbol
    shc-2
    Official Full Name
    SH2 domain-containing protein
    Primary source
    WormBase:WBGene00020867
    Locus tag
    CELE_T27F7.2
    See related
    AllianceGenome:WB:WBGene00020867
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Orthologous to human SH2D5 (SH2 domain containing 5). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See shc-2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    13
    Sequence:
    Chromosome: II; NC_003280.10 (4969163..4988940)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene SUI1 domain-containing protein Neighboring gene Mannosyltransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Microtubule severing by the katanin complex is activated by PPFR-1-dependent MEI-1 dephosphorylation. Gomes JE, et al. J Cell Biol, 2013 Aug 5. PMID 23918937, Free PMC Article
    2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    SH2 domain-containing protein
    NP_001379992.1
    • Confirmed by transcript evidence
    NP_001379993.1
    • Confirmed by transcript evidence
    NP_494915.2
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      4969163..4988940
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001393059.1 → NP_001379993.1  SH2 domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q967F3
      Conserved Domains (2) summary
      cd00173
      Location:444 → 527
      SH2; Src homology 2 (SH2) domain
      cl17171
      Location:142 → 258
      PH-like; Pleckstrin homology-like domain

    2. NM_062514.4 → NP_494915.2  SH2 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_494915.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L092
      Conserved Domains (2) summary
      cd00173
      Location:454 → 537
      SH2; Src homology 2 (SH2) domain
      cl17171
      Location:152 → 268
      PH-like; Pleckstrin homology-like domain

    3. NM_001393060.1 → NP_001379992.1  SH2 domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L091
      Conserved Domains (1) summary
      cd00173
      Location:169 → 252
      SH2; Src homology 2 (SH2) domain
    Nucleotide Protein
    Heading Accession and Version

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