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    Y54F10AL.1 GDT1 family protein [ Caenorhabditis elegans ]

    Gene ID: 175368, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y54F10AL.1
    Official Full Name
    GDT1 family protein
    Primary source
    WormBase:WBGene00021847
    Locus tag
    CELE_Y54F10AL.1
    See related
    AllianceGenome:WB:WBGene00021847
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable calcium ion transmembrane transporter activity and manganese ion transmembrane transporter activity. Predicted to be involved in Golgi calcium ion homeostasis and metal ion transport. Predicted to be located in membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including hypodermis; intestine; nervous system; pharyngeal gland cell; and reproductive system. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIk. Orthologous to human TMEM165 (transmembrane protein 165). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y54F10AL.1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    8
    Sequence:
    Chromosome: III; NC_003281.10 (2487710..2494340)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene TransThyretin-Related family domain Neighboring gene PIN domain-containing protein;PINc domain-containing protein Neighboring gene Putative phospholipase B-like 3 Neighboring gene Secreted protein Neighboring gene WD_REPEATS_REGION domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables calcium ion transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables manganese ion transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in Golgi calcium ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in Golgi calcium ion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in calcium ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in manganese ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    GDT1 family protein
    NP_497567.1
    • Confirmed by transcript evidence
    NP_497568.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      2487710..2494340
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065167.5 → NP_497568.1  GDT1 family protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497568.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9BL66
      Conserved Domains (1) summary
      COG2119
      Location:69 → 236
      Gdt1; Putative Ca2+/H+ antiporter, TMEM165/GDT1 family [General function prediction only]

    2. NM_065166.5 → NP_497567.1  GDT1 family protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497567.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KZK9
      Conserved Domains (1) summary
      COG2119
      Location:69 → 294
      Gdt1; Putative Ca2+/H+ antiporter, TMEM165/GDT1 family [General function prediction only]
    Nucleotide Protein
    Heading Accession and Version

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