U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    F07C6.4 Cytohesin Ubiquitin Protein Inducing domain-containing protein;FERM domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 178235, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    F07C6.4
    Official Full Name
    Cytohesin Ubiquitin Protein Inducing domain-containing protein;FERM domain-containing protein
    Primary source
    WormBase:WBGene00008555
    Locus tag
    CELE_F07C6.4
    See related
    AllianceGenome:WB:WBGene00008555
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in establishment of epithelial cell polarity. Orthologous to human FRMD4A (FERM domain containing 4A) and FRMD4B (FERM domain containing 4B). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See F07C6.4 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    19
    Sequence:
    Chromosome: IV; NC_003282.8 (12805925..12830115)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene LIM domain-containing protein pin-2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Bax inhibitor-1 family protein Neighboring gene TLC domain-containing protein Neighboring gene transcellular chaperone signaling (x)cross tissue

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Intestinal tube formation in Caenorhabditis elegans requires vang-1 and egl-15 signaling. Hoffmann M, et al. Dev Biol, 2010 Mar 15. PMID 20004187
    2. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in establishment of epithelial cell polarity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Cytohesin Ubiquitin Protein Inducing domain-containing protein;FERM domain-containing protein
    NP_001255674.1
    • Confirmed by transcript evidence
    NP_001293862.1
    • Confirmed by transcript evidence
    NP_001293863.1
    • Confirmed by transcript evidence
    NP_001293864.1
    • Confirmed by transcript evidence
    NP_001370283.1
    • Confirmed by transcript evidence
    NP_001379112.1
    • Confirmed by transcript evidence
    NP_502441.2
    • Confirmed by transcript evidence
    NP_502442.2
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      12805925..12830115
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001306933.4 → NP_001293862.1  FERM domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293862.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A061ACE0
      Conserved Domains (4) summary
      smart00295
      Location:18 → 219
      B41; Band 4.1 homologues
      pfam11029
      Location:829 → 906
      DAZAP2; DAZ associated protein 2 (DAZAP2)
      pfam11819
      Location:416 → 565
      DUF3338; Domain of unknown function (DUF3338)
      cl17171
      Location:215 → 360
      PH-like; Pleckstrin homology-like domain

    2. NM_001383224.2 → NP_001370283.1  FERM domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EGL0
      Conserved Domains (3) summary
      smart00295
      Location:18 → 219
      B41; Band 4.1 homologues
      pfam11819
      Location:411 → 565
      DUF3338; Domain of unknown function (DUF3338)
      cl17171
      Location:215 → 360
      PH-like; Pleckstrin homology-like domain

    3. NM_001268745.3 → NP_001255674.1  FERM domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255674.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5ECW4
      Conserved Domains (4) summary
      smart00295
      Location:18 → 219
      B41; Band 4.1 homologues
      cd13191
      Location:215 → 360
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
      pfam11029
      Location:900 → 977
      DAZAP2; DAZ associated protein 2 (DAZAP2)
      pfam11819
      Location:416 → 565
      DUF3338; Domain of unknown function (DUF3338)

    4. NM_070040.8 → NP_502441.2  FERM domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502441.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8I093
      Conserved Domains (2) summary
      smart00295
      Location:18 → 219
      B41; Band 4.1 homologues
      cl17171
      Location:215 → 359
      PH-like; Pleckstrin homology-like domain

    5. NM_001306934.3 → NP_001293863.1  FERM domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293863.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A061AIT4
      Conserved Domains (3) summary
      pfam11819
      Location:253 → 402
      DUF3338; Domain of unknown function (DUF3338)
      cl09511
      Location:6 → 56
      FERM_B-lobe; FERM domain B-lobe
      cl17171
      Location:52 → 197
      PH-like; Pleckstrin homology-like domain

    6. NM_001306935.3 → NP_001293864.1  FERM domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293864.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A061AKJ3
      Conserved Domains (4) summary
      pfam11029
      Location:666 → 743
      DAZAP2; DAZ associated protein 2 (DAZAP2)
      pfam11819
      Location:253 → 402
      DUF3338; Domain of unknown function (DUF3338)
      cl09511
      Location:6 → 56
      FERM_B-lobe; FERM domain B-lobe
      cl17171
      Location:52 → 197
      PH-like; Pleckstrin homology-like domain

    7. NM_070041.7 → NP_502442.2  Cytohesin Ubiquitin Protein Inducing domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502442.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5ECX1
      Conserved Domains (1) summary
      pfam11819
      Location:78 → 227
      DUF3338; Domain of unknown function (DUF3338)

    8. NM_001392420.1 → NP_001379112.1  Cytohesin Ubiquitin Protein Inducing domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5ECS7
      Conserved Domains (1) summary
      pfam11819
      Location:5 → 159
      DUF3338; Domain of unknown function (DUF3338)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools