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    MPK1 mitogen-activated protein kinase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837559, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MPK1
    Official Full Name
    mitogen-activated protein kinase 1
    Primary source
    TAIR:AT1G10210
    Locus tag
    AT1G10210
    See related
    Araport:AT1G10210
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATMPK1; F14N23.9; F14N23_9; MITOGEN-ACTIVATED PROTEIN KINASE; mitogen-activated protein kinase 1
    Summary
    Encodes ATMPK1.
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    Genomic context

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    See MPK1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (3349082..3351180)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene NEP-interacting protein, putative (DUF239) Neighboring gene GATA type zinc finger transcription factor family protein Neighboring gene ZCF37 Neighboring gene transmembrane protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis MAP Kinase Phosphatase 1 (AtMKP1) negatively regulates MPK6-mediated PAMP responses and resistance against bacteria. Anderson JC, et al. Plant J, 2011 Jul. PMID 21447069
    2. Diverse stress signals activate the C1 subgroup MAP kinases of Arabidopsis. Ortiz-Masia D, et al. FEBS Lett, 2007 May 1. PMID 17433310
    3. Characterization of two cDNAs that encode MAP kinase homologues in Arabidopsis thaliana and analysis of the possible role of auxin in activating such kinase activities in cultured cells. Mizoguchi T, et al. Plant J, 1994 Jan. PMID 8130795
    4. An Arabidopsis kinase cascade influences auxin-responsive cell expansion. Enders TA, et al. Plant J, 2017 Oct. PMID 28710770, Free PMC Article
    5. MAP kinase phosphatase1 and protein tyrosine phosphatase1 are repressors of salicylic acid synthesis and SNC1-mediated responses in Arabidopsis. Bartels S, et al. Plant Cell, 2009 Sep. PMID 19789277, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The data suggest a MKK3 * MPK1 * RBK1 phosphorylation cascade that may provide a dynamic module for altering cell expansion.
      Title: An Arabidopsis kinase cascade influences auxin-responsive cell expansion.
    2. MKP1 is a negative regulator of signaling pathways required for some, but not all, early and late pathogen-associated molecular pattern responses.
      Title: Arabidopsis MAP Kinase Phosphatase 1 (AtMKP1) negatively regulates MPK6-mediated PAMP responses and resistance against bacteria.
    3. MKP1 and PTP1 act redundantly to suppress salicylic acid and camalexin biosynthesis, and regulate growth homeostasis and PR gene expression in an MPK3- and MPK6-dependent manner.
      Title: MAP kinase phosphatase1 and protein tyrosine phosphatase1 are repressors of salicylic acid synthesis and SNC1-mediated responses in Arabidopsis.
    4. Regulation of AtMPK1/2 kinase activity in Arabidopsis might be under the control of signals involved in different kinds of stress.
      Title: Diverse stress signals activate the C1 subgroup MAP kinases of Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001035940.2
    NM_001331892.1
    NM_100895.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables MAP kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within auxin-activated signaling pathway TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within signal transduction IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    mitogen-activated protein kinase 1
    NP_001031017.1
    • mitogen-activated protein kinase 1 (ATMPK1); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: mitogen-activated protein kinase homolog 2 (TAIR:AT1G59580.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_172492.1
    • mitogen-activated protein kinase 1 (MPK1); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: mitogen-activated protein kinase homolog 2 (TAIR:AT1G59580.2); Has 120133 Blast hits to 118709 proteins in 4414 species: Archae - 90; Bacteria - 12052; Metazoa - 45818; Fungi - 12226; Plants - 29321; Viruses - 480; Other Eukaryotes - 20146 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      3349082..3351180
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100895.3 → NP_172492.1  mitogen-activated protein kinase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172492.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39021, Q9SY63
      UniProtKB/TrEMBL
      A0A178W6I4, B9DGP4
      Conserved Domains (1) summary
      cd07858
      Location:26 → 361
      STKc_TEY_MAPK; Catalytic domain of the Serine/Threonine Kinases, Plant TEY Mitogen-Activated Protein Kinases

    2. NM_001331892.1 → NP_001320530.1  mitogen-activated protein kinase 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39021, Q9SY63
      UniProtKB/TrEMBL
      A0A178W6I4, B9DGP4
      Conserved Domains (1) summary
      cd07858
      Location:26 → 361
      STKc_TEY_MAPK; Catalytic domain of the Serine/Threonine Kinases, Plant TEY Mitogen-Activated Protein Kinases

    3. NM_001035940.2 → NP_001031017.1  mitogen-activated protein kinase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031017.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39021, Q9SY63
      UniProtKB/TrEMBL
      A0A178W6I4, B9DGP4
      Conserved Domains (1) summary
      cd07858
      Location:26 → 361
      STKc_TEY_MAPK; Catalytic domain of the Serine/Threonine Kinases, Plant TEY Mitogen-Activated Protein Kinases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q39021.2

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