SHY2 AUX/IAA transcriptional regulator family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

Go to the top of the page Help

Official Symbol: SHY2
Official Full Name: AUX/IAA transcriptional regulator family protein
Primary source: TAIR:AT1G04240
Locus tag: AT1G04240
See related: Araport:AT1G04240
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F19P19.32; F19P19_32; IAA3; indole-3-acetic acid inducible 3; SHORT HYPOCOTYL 2
Summary: SHY2/IAA3 regulates multiple auxin responses in roots. It is induced rapidly by IAA, and has been shown to be phosphorylated by oat phytochrome A in vitro.
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See SHY2 in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 3

Sequence:: Chromosome: 1; NC_003070.9 (1128149..1129689, complement)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

ABSCISIC ACID INSENSITIVE 3 promotes auxin signalling by regulating SHY2 expression to control primary root growth in response to dehydration stress.
Title: ABSCISIC ACID INSENSITIVE 3 promotes auxin signalling by regulating SHY2 expression to control primary root growth in response to dehydration stress.
IAA3-mediated repression of PIF proteins coordinates light and auxin signaling in Arabidopsis.
Title: IAA3-mediated repression of PIF proteins coordinates light and auxin signaling in Arabidopsis.
SHY2 as a node in the regulation of root meristem development by auxin, brassinosteroids, and cytokinin.
Title: SHY2 as a node in the regulation of root meristem development by auxin, brassinosteroids, and cytokinin.
Phytochrome-interacting factor 4 (PIF4) inhibits expression of SHORT HYPOCOTYL 2 (SHY2) to promote hypocotyl growth during shade avoidance in Arabidopsis.
Title: Phytochrome-interacting factor 4 (PIF4) inhibits expression of SHORT HYPOCOTYL 2 (SHY2) to promote hypocotyl growth during shade avoidance in Arabidopsis.
SHY2 is a pivotal negative regulator of root growth, which has been demonstrated to efficiently repress transcription of major auxin transport facilitators of the PIN-FORMED (PIN) gene family, thereby restricting polar auxin transport to the root tip and in consequence auxin-driven primary root growth. Taken together, our results disclose the central low-energy activated SnRK1-C/S1-bZIP signalling module as gateway to
Title: The Arabidopsis bZIP11 transcription factor links low-energy signalling to auxin-mediated control of primary root growth.
DA1-related protein 2 (DAR2) acts downstream of cytokinin and SHY2 but upstream of PLT1/2 to affect root meristem size.
Title: DAR2 acts as an important node connecting cytokinin, auxin, SHY2 and PLT1/2 in root meristem size control.
Strigolactone signaling involves SHY2 protein activity in roots.
Title: Strigolactone signaling in the endodermis is sufficient to restore root responses and involves SHORT HYPOCOTYL 2 (SHY2) activity.
The shy2 mutations strongly elevate endogenous indole-3-acetic acid level in the roots.
Title: Multiple AUX/IAA-ARF modules regulate lateral root formation: the role of Arabidopsis SHY2/IAA3-mediated auxin signalling.
Data suggest a model in which the regulatory interactions favor BRX expression in the early proximal meristem and SHY2 prevails because of supplementary cytokinin induction in the later distal meristem.
Title: Spatio-temporal sequence of cross-regulatory events in root meristem growth.
ARR1 activates SHY2 gene, repressor of auxin signaling that negatively regulates PIN auxin transport facilitator genes: cytokinin causes auxin redistribution, prompting differentiation; auxin mediates degradation of SHY2, sustaining cell division
Title: A genetic framework for the control of cell division and differentiation in the root meristem.

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

NM_100305.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables identical protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables transcription cis-regulatory region binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within response to auxin	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

Go to the top of the page Help

Preferred Names: AUX/IAA transcriptional regulator family protein

NP_171920.1

SHORT HYPOCOTYL 2 (SHY2); FUNCTIONS IN: sequence-specific DNA binding transcription factor activity; INVOLVED IN: response to auxin stimulus, response to cyclopentenone, response to brassinosteroid stimulus; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aux/IAA-ARF-dimerisation (InterPro:IPR011525), AUX/IAA protein (InterPro:IPR003311); BEST Arabidopsis thaliana protein match is: AUX/IAA transcriptional regulator family protein (TAIR:AT5G43700.1); Has 1823 Blast hits to 1821 proteins in 83 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 1822; Viruses - 0; Other Eukaryotes - 1 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

1128149..1129689 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001331470.1 → NP_001322162.1 AUX/IAA transcriptional regulator family protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1P8AT43
NM_100305.4 → NP_171920.1 AUX/IAA transcriptional regulator family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_171920.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O04741, Q38822

UniProtKB/TrEMBL

A0A178WBD1, A0A384LAD2, A0A654E6M3, B0FV08, B0FV14, B0FV35

Conserved Domains (1) summary

pfam02309
Location:9 → 186

AUX_IAA; AUX/IAA family