U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    COG0212 NagB/RpiA/CoA transferase-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 844007, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    COG0212
    Official Full Name
    NagB/RpiA/CoA transferase-like superfamily protein
    Primary source
    TAIR:AT1G76730
    Locus tag
    AT1G76730
    See related
    Araport:AT1G76730
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    Clusters of Orthologous group 212; F28O16.10; F28O16_10
    Summary
    Encodes a paralog of ATP-dependent folate salvage enzyme 5-formyltetrahydrofolate cycloligase (5-FCL) that is targeted to chloroplasts and to be required for embryo viability and lacks 5-FCL activity.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See COG0212 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (28802753..28804858, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene egg cell-secreted-like protein (DUF1278)

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A 5-formyltetrahydrofolate cycloligase paralog from all domains of life: comparative genomic and experimental evidence for a cryptic role in thiamin metabolism. Pribat A, et al. Funct Integr Genomics, 2011 Sep. PMID 21538139, Free PMC Article
    2. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
    3. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. the 5-formyltetrahydrofolate cyclo-ligase protein from Arabidopsis thaliana lacked 5-formyltetrahydrofolate cyclo-ligase activity in vitro
      Title: A 5-formyltetrahydrofolate cycloligase paralog from all domains of life: comparative genomic and experimental evidence for a cryptic role in thiamin metabolism.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Homology

    NM_106323.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    NOT enables 5-formyltetrahydrofolate cyclo-ligase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    NagB/RpiA/CoA transferase-like superfamily protein
    NP_565139.1
    • NagB/RpiA/CoA transferase-like superfamily protein; FUNCTIONS IN: catalytic activity, ATP binding, 5-formyltetrahydrofolate cyclo-ligase activity; INVOLVED IN: folic acid and derivative biosynthetic process, metabolic process; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: 5-formyltetrahydrofolate cyclo-ligase (InterPro:IPR002698); Has 415 Blast hits to 415 proteins in 174 species: Archae - 92; Bacteria - 129; Metazoa - 119; Fungi - 6; Plants - 46; Viruses - 0; Other Eukaryotes - 23 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      28802753..28804858 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_106323.4 → NP_565139.1  NagB/RpiA/CoA transferase-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565139.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8GW33, Q9SRE0
      UniProtKB/TrEMBL
      A0A178WEK7, A0A5S9WUY5, A0A7G2E6Q4
      Conserved Domains (1) summary
      pfam01812
      Location:92 → 290
      5-FTHF_cyc-lig; 5-formyltetrahydrofolate cyclo-ligase family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SRE0.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools