U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    BPM2 BTB-POZ and MATH domain 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819793, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    BPM2
    Official Full Name
    BTB-POZ and MATH domain 2
    Primary source
    TAIR:AT3G06190
    Locus tag
    AT3G06190
    See related
    Araport:AT3G06190
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATBPM2; BTB-POZ and MATH domain 2; BTB-POZ AND MATH DOMAIN 2; F28L1.13; F28L1_13
    Summary
    Encodes a member of the MATH-BTB domain proteins (BPMs) that directly interact with and target for proteasomal degradation the class I homeobox-leucine zipper (HD-ZIP) transcription factor ATHB6. Known members include AT5G19000 (BPM1), AT3G06190 (BPM2), AT2G39760 (BPM3), AT3G03740 (BPM4), AT5G21010 (BPM5) and AT3G43700 (BPM6).
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See BPM2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    5
    Sequence:
    Chromosome: 3; NC_003074.8 (1874169..1876946, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene AP2/B3-like transcriptional factor family protein Neighboring gene Serinc-domain containing serine and sphingolipid biosynthesis protein Neighboring gene Ribosomal protein L34e superfamily protein Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene ARM repeat superfamily protein Neighboring gene AP2/B3-like transcriptional factor family protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Identification of Arabidopsis MYB56 as a novel substrate for CRL3BPM E3 ligases. Chen L, et al. Mol Plant, 2014 Oct 24. PMID 25343985
    2. MATH/BTB CRL3 receptors target the homeodomain-leucine zipper ATHB6 to modulate abscisic acid signaling. Lechner E, et al. Dev Cell, 2011 Dec 13. PMID 22172674
    3. Identification of Arabidopsis MYB56 as a novel substrate for CRL3(BPM) E3 ligases. Chen L, et al. Mol Plant, 2015 Feb. PMID 25618823
    4. Arabidopsis thaliana BTB/ POZ-MATH proteins interact with members of the ERF/AP2 transcription factor family. Weber H, et al. FEBS J, 2009 Nov. PMID 19843165
    5. Arabidopsis has two redundant Cullin3 proteins that are essential for embryo development and that interact with RBX1 and BTB proteins to form multisubunit E3 ubiquitin ligase complexes in vivo. Figueroa P, et al. Plant Cell, 2005 Apr. PMID 15772280, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. BPM2 interact with members of the ERF/AP2 transcription factor family.
      Title: Arabidopsis thaliana BTB/ POZ-MATH proteins interact with members of the ERF/AP2 transcription factor family.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_001337638.1
    NM_001337639.1
    NM_001337640.1
    NM_111494.3
    NM_202507.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to salt stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within cellular response to water deprivation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to osmotic stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    BTB-POZ and MATH domain 2
    NP_566275.1
    • BTB-POZ and MATH domain 2 (BPM2); CONTAINS InterPro DOMAIN/s: TRAF-like (InterPro:IPR008974), MATH (InterPro:IPR002083), BTB/POZ fold (InterPro:IPR011333), BTB/POZ (InterPro:IPR013069), Kelch related (InterPro:IPR013089), BTB/POZ-like (InterPro:IPR000210), TRAF-type (InterPro:IPR013322); BEST Arabidopsis thaliana protein match is: BTB-POZ and MATH domain 1 (TAIR:AT5G19000.1); Has 5905 Blast hits to 5761 proteins in 162 species: Archae - 0; Bacteria - 0; Metazoa - 4114; Fungi - 49; Plants - 1477; Viruses - 0; Other Eukaryotes - 265 (source: NCBI BLink).
    NP_974236.1
    • BTB-POZ and MATH domain 2 (BPM2); CONTAINS InterPro DOMAIN/s: TRAF-like (InterPro:IPR008974), MATH (InterPro:IPR002083), BTB/POZ fold (InterPro:IPR011333), BTB/POZ (InterPro:IPR013069), Kelch related (InterPro:IPR013089), BTB/POZ-like (InterPro:IPR000210), TRAF-type (InterPro:IPR013322); BEST Arabidopsis thaliana protein match is: BTB-POZ and MATH domain 1 (TAIR:AT5G19000.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      1874169..1876946 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111494.3 → NP_566275.1  BTB-POZ and MATH domain 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566275.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M8J9
      UniProtKB/TrEMBL
      A0A178VH59, A0A5S9X9Y1, A0A654F686
      Conserved Domains (3) summary
      cd00121
      Location:33 → 166
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
      cd18280
      Location:188 → 308
      BTB_POZ_BPM_plant; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in plant BTB/POZ-MATH (BPM) protein family
      cd14736
      Location:308 → 371
      BACK_AtBPM-like; BACK (BTB and C-terminal Kelch) domain found in plant BTB/POZ-MATH (BPM) protein family

    2. NM_001337638.1 → NP_001326823.1  BTB-POZ and MATH domain 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LQG0

    3. NM_001337639.1 → NP_001326822.1  BTB-POZ and MATH domain 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LQF9
      Conserved Domains (2) summary
      cd00121
      Location:33 → 166
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
      cl38908
      Location:188 → 257
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily

    4. NM_202507.1 → NP_974236.1  BTB-POZ and MATH domain 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974236.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4JAT1
      Conserved Domains (3) summary
      smart00225
      Location:203 → 260
      BTB; Broad-Complex, Tramtrack and Bric a brac
      cd00121
      Location:33 → 166
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
      pfam00651
      Location:192 → 260
      BTB; BTB/POZ domain

    5. NM_001337640.1 → NP_001326821.1  BTB-POZ and MATH domain 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VH59, A0A1I9LQF8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M8J9.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools