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    Trimeric LpxA-like enzyme [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827556, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Trimeric LpxA-like enzyme
    Primary source
    TAIR:AT4G18300
    Locus tag
    AT4G18300
    See related
    Araport:AT4G18300
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T9A21.150; T9A21_150
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    1
    Sequence:
    Chromosome: 4; NC_003075.7 (10118784..10121258)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene glycine-rich cell wall protein-like protein Neighboring gene potassium channel KAT1-like protein Neighboring gene uncharacterized protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Capturing the phosphorylation and protein interaction landscape of the plant TOR kinase. Van Leene J, et al. Nat Plants, 2019 Mar. PMID 30833711
    2. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_117940.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables translation initiation factor binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Trimeric LpxA-like enzyme
    NP_193564.1
    • Trimeric LpxA-like enzyme; FUNCTIONS IN: binding, transferase activity, translation initiation factor activity, nucleotidyltransferase activity; INVOLVED IN: biosynthetic process, regulation of translational initiation; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Trimeric LpxA-like (InterPro:IPR011004), eIF4-gamma/eIF5/eIF2-epsilon (InterPro:IPR003307), Armadillo-type fold (InterPro:IPR016024), Nucleotidyl transferase (InterPro:IPR005835); BEST Arabidopsis thaliana protein match is: Trimeric LpxA-like enzyme (TAIR:AT2G34970.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      10118784..10121258
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_117940.2 → NP_193564.1  Trimeric LpxA-like enzyme [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193564.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9XTM0, A0A654FQY7, O49733
      Conserved Domains (3) summary
      cd05787
      Location:339 → 417
      LbH_eIF2B_epsilon; eIF-2B epsilon subunit, central Left-handed parallel beta-Helix (LbH) domain: eIF-2B is a eukaryotic translation initiator, a guanine nucleotide exchange factor (GEF) composed of five different subunits (alpha, beta, gamma, delta and epsilon). eIF2B is ...
      cd04197
      Location:24 → 236
      eIF-2B_epsilon_N; The N-terminal domain of epsilon subunit of the eIF-2B is a subfamily of glycosyltransferase 2
      cd11558
      Location:539 → 702
      W2_eIF2B_epsilon; C-terminal W2 domain of eukaryotic translation initiation factor 2B epsilon
    Nucleotide Protein
    Heading Accession and Version

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