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    APT3 adenine phosphoribosyl transferase 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828353, updated on 18-Sep-2024

    Summary

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    Official Symbol
    APT3
    Official Full Name
    adenine phosphoribosyl transferase 3
    Primary source
    TAIR:AT4G22570
    Locus tag
    AT4G22570
    See related
    Araport:AT4G22570
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    adenine phosphoribosyl transferase 3; F7K2.150; F7K2_150
    Summary
    Encodes an adenine phosphoribosyltransferase (APT; EC 2.4.2.7), which is a constitutively expressed enzyme involved in the one-step salvage of adenine to AMP. APT3 has higher affinity for zeatin, isopentenyladenine and benzyladenine than APT1 but lower Vmax than APT1.
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    Genomic context

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    See APT3 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    6
    Sequence:
    Chromosome: 4; NC_003075.7 (11882066..11885533, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Phosphatidic acid phosphatase (PAP2) family protein Neighboring gene sulfated surface-like glycoprotein Neighboring gene Exostosin family protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Adenine phosphoribosyltransferase isoforms of Arabidopsis and their potential contributions to adenine and cytokinin metabolism. Allen M, et al. Physiol Plant, 2002 May. PMID 12010467
    2. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    3. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    4. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001341554.1
    NM_118383.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables adenine phosphoribosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in AMP salvage IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within adenine salvage TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    adenine phosphoribosyl transferase 3
    NP_193988.1
    • adenine phosphoribosyl transferase 3 (APT3); CONTAINS InterPro DOMAIN/s: Adenine phosphoribosyl transferase (InterPro:IPR005764), Phosphoribosyltransferase (InterPro:IPR000836); BEST Arabidopsis thaliana protein match is: adenine phosphoribosyl transferase 4 (TAIR:AT4G12440.2); Has 8946 Blast hits to 8945 proteins in 2488 species: Archae - 280; Bacteria - 6058; Metazoa - 171; Fungi - 181; Plants - 166; Viruses - 0; Other Eukaryotes - 2090 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      11882066..11885533 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118383.4 → NP_193988.1  adenine phosphoribosyl transferase 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193988.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LG17, Q9SUW2
      UniProtKB/TrEMBL
      A0A178V1I0, A0A5S9XVQ8, A0A7G2F048
      Conserved Domains (1) summary
      PLN02293
      Location:1 → 183
      PLN02293; adenine phosphoribosyltransferase

    2. NM_001341554.1 → NP_001329095.1  adenine phosphoribosyl transferase 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B6N4
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SUW2.1

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