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    ORC5 origin recognition complex protein 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829114, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ORC5
    Official Full Name
    origin recognition complex protein 5
    Primary source
    TAIR:AT4G29910
    Locus tag
    AT4G29910
    See related
    Araport:AT4G29910
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATORC5; EMB2798; EMBRYO DEFECTIVE 2798; F27B13.150; F27B13_150; origin recognition complex protein 5; ORIGIN RECOGNITION COMPLEX SUBUNIT 5
    Summary
    Origin Recognition Complex subunit 5. Involved in the initiation of DNA replication. Interacts strongly with all ORC subunits.
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    Genomic context

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    See ORC5 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    5
    Sequence:
    Chromosome: 4; NC_003075.7 (14627885..14630804, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene autoinhibited Ca(2+)-ATPase 10 Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The genes encoding Arabidopsis ORC subunits are E2F targets and the two ORC1 genes are differently expressed in proliferating and endoreplicating cells. Diaz-Trivino S, et al. Nucleic Acids Res, 2005. PMID 16179646, Free PMC Article
    2. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_001341981.1
    NM_119137.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA replication ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    part_of origin recognition complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of origin recognition complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    origin recognition complex protein 5
    NP_194720.2
    • origin recognition complex protein 5 (ORC5); CONTAINS InterPro DOMAIN/s: Origin recognition complex, subunit 5 (InterPro:IPR020796); Has 287 Blast hits to 283 proteins in 127 species: Archae - 0; Bacteria - 0; Metazoa - 140; Fungi - 92; Plants - 43; Viruses - 0; Other Eukaryotes - 12 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      14627885..14630804 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119137.5 → NP_194720.2  origin recognition complex protein 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194720.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6EWX0, Q9SZR2
      UniProtKB/TrEMBL
      A0A178UTP1
      Conserved Domains (3) summary
      COG1474
      Location:53 → 258
      CDC6; Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]
      pfam13191
      Location:55 → 223
      AAA_16; AAA ATPase domain
      pfam14630
      Location:245 → 531
      ORC5_C; Origin recognition complex (ORC) subunit 5 C-terminus

    2. NM_001341981.1 → NP_001328994.1  origin recognition complex protein 5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B6D3, A0A5S9XX71, A0A654FUJ5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6EWX0.1

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