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    GYF domain-containing protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834307, updated on 18-Sep-2024

    Summary

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    Official Full Name
    GYF domain-containing protein
    Primary source
    TAIR:AT5G42950
    Locus tag
    AT5G42950
    See related
    Araport:AT5G42950
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MBD2.15; MBD2_15
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    10
    Sequence:
    Chromosome: 5; NC_003076.8 (17224270..17231384)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene RING/U-box superfamily protein Neighboring gene ncRNA Neighboring gene inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein (DUF784) Neighboring gene inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein (DUF784)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulation of plant immune receptor accumulation through translational repression by a glycine-tyrosine-phenylalanine (GYF) domain protein. Wu Z, et al. Elife, 2017 Mar 31. PMID 28362261, Free PMC Article
    2. EXA1, a GYF domain protein, is responsible for loss-of-susceptibility to plantago asiatica mosaic virus in Arabidopsis thaliana. Hashimoto M, et al. Plant J, 2016 Oct. PMID 27402258
    3. PARG1 and EXA1 genes as possible components of the facultative epigenetic control of plant development. Kupriyanova E, et al. Physiol Plant, 2023 Jul-Aug. PMID 37350155
    4. The GYF domain protein PSIG1 dampens the induction of cell death during plant-pathogen interactions. Matsui H, et al. PLoS Genet, 2017 Oct. PMID 29073135, Free PMC Article
    5. Interaction of EXA1 and eIF4E Family Members Facilitates Potexvirus Infection in Arabidopsis thaliana. Nishikawa M, et al. J Virol, 2023 Jun 29. PMID 37199623, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. PARG1 and EXA1 genes as possible components of the facultative epigenetic control of plant development.
      Title: PARG1 and EXA1 genes as possible components of the facultative epigenetic control of plant development.
    2. Interaction of EXA1 and eIF4E Family Members Facilitates Potexvirus Infection in Arabidopsis thaliana.
      Title: Interaction of EXA1 and eIF4E Family Members Facilitates Potexvirus Infection in Arabidopsis thaliana.
    3. PSIG1 interacts with SMG7, which plays a role in nonsense-mediated RNA decay (NMD), and the smg7-4 mutant allele mimics the cell death phenotype of the psig1 mutants. [PSIG1]
      Title: The GYF domain protein PSIG1 dampens the induction of cell death during plant-pathogen interactions.
    4. Genetic and biochemical analysis revealed that loss of EXA1 leads to heightened nucleotide-binding leucine-rich repeat (NLR) receptor accumulation and enhanced resistance against virulent pathogens. [EXA1]
      Title: Regulation of plant immune receptor accumulation through translational repression by a glycine-tyrosine-phenylalanine (GYF) domain protein.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_123660.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mRNA binding HDA PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within defense response to virus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of defense response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    GYF domain-containing protein
    NP_199109.1
    • GYF domain-containing protein; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: GYF (InterPro:IPR003169); BEST Arabidopsis thaliana protein match is: GYF domain-containing protein (TAIR:AT1G24300.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      17224270..17231384
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_123660.3 → NP_199109.1  GYF domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199109.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FMM3
      UniProtKB/TrEMBL
      A0A178UGK6
      Conserved Domains (1) summary
      cd00072
      Location:546 → 603
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FMM3.1

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